- Aromatase inhibition in ovarian cancer: repeated signals of efficacy but tools for patient selection remain elusive
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Gourley C
- KMID: 2457161
- J Gynecol Oncol.
- 2019 Sep;30(5):e98.
- doi: 10.3802/jgo.2019.30.e98
No abstract available. -
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- Appropriate Testosterone-to-Estradiol Ratios for Aromatase Inhibitor Usage in Oligoasthenospermic Men
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Lee JS, Park YS, Lee JS, Seo JT
- KMID: 2298695
- Korean J Androl.
- 2004 Apr;22(1):31-35.
PURPOSE: We investigated whether oligospermic or asthenospermic men have decreased testosterone-to-estradiol (TE) ratios and whether this condition can be corrected with an oral aromatase inhibitor. We also determined the predictive... -
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- Survival Benefit of Zoledronic Acid in Postmenopausal Breast Cancer Patients Receiving Aromatase Inhibitors
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Ahn SG, Kim SH, Lee HM, Lee SA, Jeong J
- KMID: 2176126
- J Breast Cancer.
- 2014 Dec;17(4):350-355.
- doi: 10.4048/jbc.2014.17.4.350
PURPOSE: A growing body of evidence indicates that zoledronic acid (ZA) can improve the clinical outcome in patients with breast cancer and low estrogen levels. In the present study, we... -
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- Effect of Potent Aromatase Inhibitor (Letrozole) on Bone Maturation and Predicted Adult Height in Boys with Early Puberty
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Kim JY, Cha EY, Jung MH, Lee BC
- KMID: 1510409
- J Korean Soc Pediatr Endocrinol.
- 2006 Jun;11(1):40-44.
PURPOSE: We evaluated the effect of potent aromatase inhibitor (Letrozole) on the rate of bone maturation and an increase in predicted adult height (PAH) in boys with early puberty. METHODS: Nine... -
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- Expression of aromatase in endometiosis and its relation to clinical laboratory and surgical parameters
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Lee IH, Kim DH, Noh JH, Koh JW, Kim YB
- KMID: 2273862
- Korean J Obstet Gynecol.
- 2010 Apr;53(4):346-353.
- doi: 10.5468/kjog.2010.53.4.346
OBJECTIVE: Aromatase is the key enzyme for the conversion of C19 steroids into estrogen in certain human tissues. We studied to evaluate the aromatase expression in eutopic endometirum and endometriotic... -
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- Efficacy of Combined Aromatase Inhibitor and Luteinizing Hormone-Releasing Hormone Agonist in Premenopausal Metastatic Breast Cancer
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Kim SH, Choi J, Park CS, Kim HA, Noh WC, Seong MK
- KMID: 2434904
- J Breast Dis.
- 2018 Dec;6(2):46-51.
- doi: 10.14449/jbd.2018.6.2.46
PURPOSE: Endocrine therapy is the preferred treatment for hormone receptor (HR)-positive metastatic breast cancer (MBC). We investigated the efficacy of combined aromatase inhibitor (AI) and luteinizing hormone-releasing hormone (LHRH) agonist... -
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- Aromatase inhibitor-associated musculoskeletal symptoms: incidence and associated factors
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Park JY, Lee SK, Bae SY, Kim J, Kim MK, Kil WH, Lee JE, Nam SJ
- KMID: 2324873
- J Korean Surg Soc.
- 2013 Nov;85(5):205-211.
PURPOSE: Arthralgia is the most common side effect in breast cancer patients receiving aromatase inhibitor (AI) therapy. Few studies have evaluated the risk factors, onset, and incidence of musculoskeletal pain... -
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- Expression pattern of Aromatase Cytochrome P450 in Adenomyosis
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Lee YJ, Kim JY, Park YS, Kim YM, Jang JB, Cho DJ, Kim JW, Yang WI
- KMID: 2019491
- Korean J Obstet Gynecol.
- 2004 Mar;47(3):531-536.
OBJECTIVE: To determine whether local estrogen production takes place in adenomyosis and in normal endometrium. METHODS: The study included 23 cases of adenomyosis and 17 cases of normal uterine endometrium obtained... -
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- Gonadotropin-releasing hormone agonist treatments reduce aromatase and cyclooxygenase-2 in ovarian endometrioma and eutopic endometium in women with endometriosis
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Kim YA, Kim MR, Lee JH, Ahn ST, Kim JY, Hwang KJ, Lee ES
- KMID: 1993040
- Korean J Obstet Gynecol.
- 2007 Feb;50(2):314-321.
OBJECTIVE: We investigated whether GnRH agonists reduce aromatase cytochrome P450 and cyclooxygenase-2 by direct action in the eutopic endometrium of endometriosis and ovarian endometrioma. METHODS: Endometrial specimens and endometriotic tissues... -
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- Therapy for idiopathic precocious puberty in children
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Shim KS, Kim JT
- KMID: 2191180
- J Korean Med Assoc.
- 2011 Sep;54(9):953-956.
- doi: 10.5124/jkma.2011.54.9.953
The incidence of idiopathic precocious puberty is rapidly increasing in Korea. The most common medication used for treatment is a gonadotropin releasing hormone agonist. However, there is some debate regarding... -
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- Gonadotropin-releasing Hormone Agonist Plus Aromatase Inhibitor in the Treatment of Uterine Leiomyoma in Near Menopause Patient: A Case Series Study
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Moradan S
- KMID: 2429222
- J Menopausal Med.
- 2018 Apr;24(1):62-66.
- doi: 10.6118/jmm.2018.24.1.62
OBJECTIVES: There are many drugs for of symptomatic fibroids. Gonadotropin-releasing hormone (GnRH) agonists are the well known drugs. Also, aromatase inhibitors are effective. All published studies surveyed the effect of... -
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- The Effectiveness of Aromatase Inhibitor in Infertile Male
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Lee JS, Han KR, Park YS, Seo JT
- KMID: 1979049
- Korean J Fertil Steril.
- 2003 Jun;30(2):135-140.
OBJECTIVE: We investigated whether serum testosterone to estradiol ratio was decreased in infertile men and whether this condition can be corrected with oral aromatase inhibitor. METHOD: The serum testosterone to estradiol... -
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- A Case of Radiation Recall Dermatitis after Hormonal Therapy of Letrozol (Femara(R))
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Ahn JY, Kim JY, Seo SJ, Hong CK, Song KY
- KMID: 2302361
- Korean J Dermatol.
- 2006 Jan;44(1):83-85.
Radiation recall dermatitis gap (RRD) is the development of an inflammatory reaction throughout a previously irradiated area, precipitated by the administration of certain drugs. Usually chemotherapeutic agents have been associated... -
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- Recovery of Ovarian Function with Aromatase Inhibitors: In Young Breast Cancer Patients (<45) with Chemotherapy-induced Amenorrhea
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Lee JH, Shin DS, Kim HA, Kim YH, Paik NS, Moon NM, Noh WC
- KMID: 1485106
- J Breast Cancer.
- 2008 Sep;11(3):133-138.
- doi: 10.4048/jbc.2008.11.3.133
PURPOSE: The role and safety of aromatase inhibitors (AIs) in young breast cancer patients with chemotherapy-induced amenorrhea (CIA) has not been established. The goal of this study was to investigate... -
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- Effectiveness of bisphosphonate combined with activated vitamin D in patients with aromatase inhibitor-induced osteoporosis after breast cancer operation
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Tanaka M, Itoh S, Takeuchi Y
- KMID: 2437291
- Osteoporos Sarcopenia.
- 2018 Sep;4(3):111-117.
- doi: 10.1016/j.afos.2018.08.002
OBJECTIVES: We compared the effectiveness of bisphosphonates combined with activated vitamin D administered for therapy of aromatase inhibitor-induced osteoporosis after a breast cancer operation and primary postmenopausal osteoporosis through propensity... -
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- The effects of the standardized extracts of Ginkgo biloba on steroidogenesis pathways and aromatase activity in H295R human adrenocortical carcinoma cells
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Kim M, Park YJ, Ahn H, Moon B, Chung KH, Oh SM
- KMID: 2469666
- Environ Health Toxicol.
- 2016 ;31(1):e2016010.
- doi: 10.5620/eht.e2016010
OBJECTIVES: Aromatase inhibitors that block estrogen synthesis are a proven first-line hormonal therapy for postmenopausal breast cancer. Although it is known that standardized extract of Ginkgo biloba (EGb761) induces anti-carcinogenic... -
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- Impact of hormonal therapy and other adjuvant therapies on contralateral breast volume change after implant-based breast reconstruction
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Park JY, Chung JH, Lee HC, Lee BI, Park SH, Yoon ES
- KMID: 2422139
- Arch Plast Surg.
- 2018 Sep;45(5):432-440.
- doi: 10.5999/aps.2018.00563
BACKGROUND: Adjuvant therapy after breast surgery, including tamoxifen or aromatase inhibitors, improves the postoperative outcomes and long-term survival of breast cancer patients. The aim of this study was to determine... -
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- Personalized therapy for advanced breast cancer using molecular signatures
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Jung KH
- KMID: 2305798
- Korean J Med.
- 2009 Jul;77(1):26-34.
In Korea, breast cancer is the second common cancer in women and many patients suffer from metastatic disease after surgery and adjuvant therapy. Metastatic breast cancer is unlikely to be... -
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- Peroxisome proliferator-activated receptor gamma agonist suppresses human telomerase reverse transcriptase expression and aromatase activity in eutopic endometrial stromal cells from endometriosis
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Chang HJ, Lee JH, Hwang KJ, Kim MR, Yoo JH
- KMID: 1493212
- Clin Exp Reprod Med.
- 2013 Jun;40(2):67-75.
- doi: 10.5653/cerm.2013.40.2.67
OBJECTIVE: To investigate the effect of peroxisome proliferator activated receptor gamma (PPARgamma) agonist on the cell proliferation properties and expression of human telomerase reverse transcriptase (hTERT) and aromatase in cultured... -
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- The Role of Androgen in the Adipose Tissue of Males
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Lee HK, Lee JK, Cho B
- KMID: 2320841
- World J Mens Health.
- 2013 Aug;31(2):136-140.
Adipose tissue, where various metabolic hormones are secreted, plays a role in metabolizing different substances including androgen. Within fat tissue, enzymes such as aromatase and aldo-keto reductase 1C are responsible... -
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