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Apolipoprotein E Genetic Polymorphism and Diabetic Microangiopathy in Type 2 Diabetic Patients

Park JS, Nam JY, Kim CS, Kim DM, Cho MH, Park J, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC

  • KMID: 2008179
  • J Korean Diabetes Assoc.
  • 2004 Dec;28(6):511-520.
BACKGROUND: The pathophysiological causes for the development and progression of diabetic microangiopathy are not well known, but the apo E genetic polymorphism has been proposed to be involved in the...
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Apolipoprotein E and ACE genetic polymorphism and nephropathy in type 2 diabetic patients

Park JS, Nam JY, Kim CS, Kim DM, Cho MH, Park J, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC

  • KMID: 2252436
  • Korean J Med.
  • 2005 May;68(5):511-518.
BACKGROUND: The aim of this study was to investigate the association between apo E and ACE genetic polymorphism and diabetic nephropathy. METHODS: One hundred eighteen patients with type 2 diabetes who...
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Blood Lipid Levels, Nutrient Intakes and Health-Related Lifestyles of Industrial Male Workers According to Apolipoprotein E Polymorphisms

Park YK, Cho SW, Kang JY, Paek YM, Sung SH, Choi TI

  • KMID: 2239193
  • Korean J Community Nutr.
  • 2008 Oct;13(5):713-722.
The purpose of this study was to investigate the association among nutrient intakes and health-related lifestyles with cardiovascular disease risk assessed by blood lipid profile according to Apolipoprotein E genotypes....
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Type III hyperlipoproteinemia associated with generalized tuberoeruptive xanthomas

Lim H, Kim DS

  • KMID: 2226040
  • Korean J Clin Pathol.
  • 2001 Aug;21(4):269-273.
A 61-year-old female patient presented with the type III hyperlipoproteinemia (HLP) in association with generalized eruptive and tuberous xanthomas. She had hypercholesterolemia and hypertriglyceridemia, and extensive coronary atherosclerosis. Further studies...
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Apolipoprotein E Polymorphism in Patients with Ischemic Cerebrovascular Disease

Park MH, Koh SB, Kim BJ, Park MK, Park KW, Lee DH

  • KMID: 2188674
  • J Korean Geriatr Soc.
  • 2001 Jun;5(2):151-158.
BACKGROUND: The possible role of apolipoprotein E (APOE for gene, apoE for protein) allele in atherosclerotic diseases is not clearly understood. For the putative role of APOE genotypes, we examined...
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Association of apolipoprotein E polymorphisms with serum lipid profiles in obese adolescent

Yoon JM, Lim JW, Cheon EJ, Ko KO

PURPOSE: Apolipoprotein E (Apo E) plays a major role in lipoprotein metabolism and lipid transport. Many investigators have described that Apo E polymorphisms is one of the most important genetic...
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Apolipoprotein E Genotyping in the Diagnosis and Differential Diagnosis of Alzheimer's Disease

Bang OY, Kwak YT

  • KMID: 2065449
  • J Korean Neurol Assoc.
  • 2000 Sep;18(5):568-574.
BACKGROUND: There is a growing interest in the use of genetic markers in predicting the various types of dementia such as Alzheimer's disease (AD) and vascular dementia (VD). It is...
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Gestational hyperlipidemia and acute pancreatitis with underlying partial lipoprotein lipase deficiency and apolipoprotein E3/E2 genotype

Han DH, Moh IH, Kim DM, Ihm SH, Choi MG, Yoo HJ, Hong EG

We report the case of a patient who experienced extreme recurrent gestational hyperlipidemia. She was diagnosed with partial lipoprotein lipase (LPL) deficiency but without an associated LPL gene mutation in...
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An Association Study of Apolipoprotein E Gene Polymorphism and Cataracts

Chi M, Im JS, Paik HJ

  • KMID: 2337936
  • J Korean Ophthalmol Soc.
  • 2011 Apr;52(4):420-428.
PURPOSE: To evaluate the association of apolipoprotein E (APOE) polymorphism and cataracts in the Korean population. METHODS: The present research included participants from a population-based study in Incheon, Korea. A sample...
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Polymorphisms of Apolipoprotein B and Apolipoprotein E in Hypobetalipoproteinemic Korean

Kim JH, Lim HS, Kwon OH

  • KMID: 2239628
  • Korean J Lab Med.
  • 2002 Dec;22(6):388-394.
BACKGROUND: Hypobetalipoproteinemia (HBL) is characterized by plasma concentration of lowdensity lipoprotein cholesterol below the fifth percentile in a healthy population. It has been suggested that HBL may be associated with...
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Influences of the Apolipoprotein E Polymorphism on the Development of Coronary Artery Disease and on Serum Lipids in the Korean Males

Ryu JC, Kim DK, Kim JW, Park WH, Choi JS, Choo JA, Choi YR, Kim MK, Cho BR, Gwon HC, Park SW, Kim JS, Lee SH, Hong KP, Kim DW, Park JE, Lee WR

BACKGROUND: Apo E lipoprotein is polymorphic and exists in three common isoforms (E2, E3 and E4), which are the gene products of three apo E alleles, e2, e3 and e4....
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Analysis of the APOE Alleles in Mental Retardation without Chromosome Anomaly

Park JS, Kim DK

  • KMID: 1514937
  • Korean J Anat.
  • 2003 Apr;36(2):155-158.
APOE (apolipoprotein E) has been as a risk factor for Alzheimer's disease. Studies demonstrated that there was no significant differences in APOE distribution compared with controls and there was also...
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Apolipoprotein E Phenotypes and the Relationship Among Lipid Levels, Nutrient Intakes, Lifestyles and Risk Factors Between Subjects with and without Hyperlipidemic Risk

Lee JE, Cho SW, Kang JY, Paek YM, Choi CS, Park YK, Choi TI

  • KMID: 2265670
  • Korean J Nutr.
  • 2008 Jul;41(5):402-413.
This study was performed to investigate Apolipoprotein E phenotypes and the relationship among lipid levels, nutrient intakes, lifestyles and risk factors between subjects with and without hyperlipidemic risk. The data...
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Evaluation of Lipids According to Apo E Genotype in Normal Control and Hyperlipidemic Patients

Kim HT, Park MJ, Lee KM

  • KMID: 2287738
  • J Clin Pathol Qual Control.
  • 1999 Dec;21(2):265-273.
BACKGROUND: Apolipoprotein E (Apo E) plays a central role in the hepatic clearance of Apo E rich lipoprotein (VLDL, chylomicron remnant, intermediate density lipoprotein) through LDL receptor. Apo E is...
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Discrepancy in Genotyping of Apolipoprotein E between Allele-Specific PCR and Fluorescence Resonance Energy Transfer or Sequencing

Park CH, Lee ST, Ki CS, Kim JW

The human apolipoprotein E (APOE) gene contains several single-nucleotide polymorphisms (SNPs) that are distributed across the gene. The genotype of the APOE gene has important implications as a risk factor...
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Relationships of Apolipoprotein E Genotypes with Vascular Risk Factors in Patients with Alzheimer's Disease

Son EJ, Kim JM, Kim YS, Kim BC, Kim MK, Cho KH

  • KMID: 1616347
  • J Korean Neurol Assoc.
  • 2003 Feb;21(1):41-45.
BACKGROUND: Apolipoprotein E-epsilon4 (APOE-epsilon4) is a known genetic risk factor for Alzheimer's disease (AD), but its relationship with vascular risk factors is still controversial. METHODS: We retrospectively studied 56 probable...
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Association of Apolipoprotein E Gene Polymorphism With Cognitive Function of the Elderly Residents in a Rural Community

Kwon OD, Choi SY, Park JH, Yoon CH, Kwon HH, Shin IH

  • KMID: 2191918
  • J Korean Neurol Assoc.
  • 2009 Nov;27(4):362-368.
BACKGROUND: It is not clear whether polymorphism of the apolipoprotein E (ApoE) gene influences the cognition of community residents. The aim of this study was to establish the association between...
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Risk Factors of Cardiovascular Disease in Korean Exceptional Longevity

Kwon IS, Kim CH, Ko HS, Cho SI, Choi YH, Park SC

  • KMID: 2338392
  • J Korean Geriatr Soc.
  • 2005 Dec;9(4):251-265.
BACKGROUND: It has been shown that subjects with exceptional longevity and their offsprings have a lower incidence and delayed onset of age-related diseases. Cardiovascular protective effect through over-presentation of Apo...
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