- Paclitaxel inhibits the hyper-activation of spleen cells by lipopolysaccharide and induces cell death
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Kim HJ, Joo HG
- KMID: 2412600
- J Vet Sci.
- 2016 Dec;17(4):453-458.
- doi: 10.4142/jvs.2016.17.4.453
Paclitaxel was isolated from the bark of the Pacific yew, Taxus brevifolia, and used as an anticancer agent. Paclitaxel prevents cancer cell division by inhibiting spindle fiber function, inducing cell... -
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- Antiproliferative effect of basic fibroblast growth factor-saporin mitotoxin on keratocytes in culture
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Wee WR, Parandoosh Z, Sakamoto T, Caton M, Nova M, McDonnell
- KMID: 1735150
- Korean J Ophthalmol.
- 1996 Jun;10(1):1-7.
- doi: 10.3341/kjo.1996.10.1.1
We evaluated the effect of the conjugate of basic fibroblast growth factor (FGF2) and saporin (FGF2-SAP) on proliferation of cultured keratocytes. Cultured rabbit and human keratocytes were incubated in medium... -
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- Blockade of VEGFR-1 and VEGFR-2 Enhances Paclitaxel Sensitivity in Gastric Cancer Cells
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Hwang JE, Lee JH, Park MR, Kim DE, Bae WK, Shim HJ, Cho SH, Chung IJ
- KMID: 1503899
- Yonsei Med J.
- 2013 Mar;54(2):374-380.
- doi: 10.3349/ymj.2013.54.2.374
PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) increases transcription of the vascular endothelial growth factor (VEGF) gene. Inhibition of VEGF abolishes VEGF mediated induction of HIF-1alpha. Recent reports suggested that HIF-1alpha also mediated... -
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- Gossypol acetic acid induces apoptosis in RAW264.7 cells via a caspase-dependent mitochondrial signaling pathway
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Deng S, Yuan H, Yi J, Lu Y, Wei Q, Guo C, Wu J, Yuan L, He Z
- KMID: 1705558
- J Vet Sci.
- 2013 Sep;14(3):281-289.
- doi: 10.4142/jvs.2013.14.3.281
To investigate the effects of gossypol acetic acid (GA) on proliferation and apoptosis of the macrophage cell line RAW264.7 and further understand the possible underlying mechanism responsible for GA-induced cell... -
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- Altered maturation of dendritic cells by taxol, an anticancer drug
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Joo HG
- KMID: 1089602
- J Vet Sci.
- 2003 Dec;4(3):229-234.
Taxol is a clinically useful anticancer drug against a variety of cancers. Although it has been known that taxol induces the apoptosis of cancer cells through cytochrome C release and... -
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- Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung carcinoma cells
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Cho HS, Chang SH, Chung YS, Shin JY, Park SJ, Lee ES, Hwang SK, Kwon JT, Tehrani AM, Woo M, Noh MS, Hanifah H, Jin H, Xu CX, Cho MH
- KMID: 1089342
- J Vet Sci.
- 2009 Mar;10(1):23-28.
- doi: 10.4142/jvs.2009.10.1.23
Tetrandrine (TET), a bis-benzylisoquinoline alkaloid from the root of Stephania tetrandra, is known to have anti-tumor activity in various malignant neoplasms. However, the precise mechanism by which TET inhibits tumor... -
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