- Application of bispecific antibody against antigen and hapten for immunodetection and immunopurification
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Kim H, Park S, Lee HK, Chung J
- KMID: 2154262
- Exp Mol Med.
- 2013 Sep;45(9):e43.
We present a bispecific antibody that recognizes an antigen and a hapten and can be applied to various biological assays, including immunoblotting and immunoprecipitation. In immunoblot analysis of serum, an... -
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- DNA-mediated immunization of mice with plasmid encoding HBs antigen
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Yoon SJ, Park JW, Ahn SY, Choe BK, Suh MH
- KMID: 648079
- J Korean Med Sci.
- 1999 Apr;14(2):187-192.
- doi: 10.3346/jkms.1999.14.2.187
In order to develop an experimental DNA vaccine for the prevention and treatment of hepatitis B virus infection, hepatitis B virus surface antigen (HBsAg) DNA was subcloned into an E.... -
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- Antigenic relationship between mugwort and ragweed pollens by crossed immunoelectrophoresis
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Park HS, Kim MJ, Moon HB
- KMID: 644797
- J Korean Med Sci.
- 1994 Jun;9(3):213-217.
- doi: 10.3346/jkms.1994.9.3.213
Mugwort and ragweed pollens have been considered as important respiratory allergens in Korea. These two pollens are abundant in the air of Seoul from August through October. Many ragweed-sensitive patients... -
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- Monitoring antibody titers to recombinant Core-NS3 fusion polypeptide is useful for evaluating hepatitis C virus infection and responses to interferon-alpha therapy
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Park YM, Byun BH, Choi JY, Bae SH, Kim BS, So HS, Ryu WS
- KMID: 648075
- J Korean Med Sci.
- 1999 Apr;14(2):165-170.
- doi: 10.3346/jkms.1999.14.2.165
To evaluate the clinical feasibility of the antibody titer against a chimeric polypeptide (named Core 518), in which a domain of Core and NS3 of hepatitis C virus (HCV) was... -
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- Comparative Quantitative Analysis of Cluster of Differentiation 45 Antigen Expression on Lymphocyte Subsets
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Im M, Chae H, Kim T, Park HH, Lim J, Oh EJ, Kim Y, Park YJ, Han K
- KMID: 1735845
- Korean J Lab Med.
- 2011 Jul;31(3):148-153.
- doi: 10.3343/kjlm.2011.31.3.148
BACKGROUND: Since the recent introduction of radioimmunotherapy (RIT) using antibodies against cluster of differentiation (CD) 45 for the treatment of lymphoma, the clinical significance of the CD45 antigen has been... -
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- 4-1BB (CD137) signals depend upon CD28 signals in alloimmune responses
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Lee EA, Kim JE, Seo JH, Kwon BS, Nam SH, Kwon B, Cho HR
- KMID: 1115938
- Exp Mol Med.
- 2006 Dec;38(6):606-615.
Our previous study has demonstrated that there is a significant delay of Balb/c cardiac allograft rejection in the C57BL/6 4-1BB-deficient knockout recipient. In this study, we examined the effect of... -
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- Podoplanin, alpha-Smooth Muscle Actin or S100A4 Expressing Cancer-Associated Fibroblasts Are Associated with Different Prognosis in Colorectal Cancers
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Choi SY, Sung R, Lee SJ, Lee TG, Kim N, Yoon SM, Lee EJ, Chae HB, Youn SJ, Park SM
- KMID: 1793043
- J Korean Med Sci.
- 2013 Sep;28(9):1293-1301.
- doi: 10.3346/jkms.2013.28.9.1293
The interactions between the tumor microenvironment and tumor cells determine the behavior of the primary tumors. Whether cancer-associated fibroblasts (CAF) have a tumor progressive or a protective role likely depends... -
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- Prostaglandin E2 and Interleukin-1beta Reduce E-cadherin Expression by Enhancing Snail Expression in Gastric Cancer Cells
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Jee YS, Jang TJ, Jung KH
- KMID: 1782129
- J Korean Med Sci.
- 2012 Sep;27(9):987-992.
- doi: 10.3346/jkms.2012.27.9.987
Inflammation is closely related to the progression of cancer as well as tumorigenesis. Here, we investigated the effect of prostaglandin E2 (PGE2) and interleukin-1beta (IL-1beta) on E-cadherin expression in SNU719... -
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- Current Status and Vaccine Indication for Hepatitis A Virus Infection in Korea
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Jeong SH
- KMID: 1767537
- Korean J Gastroenterol.
- 2008 Jun;51(6):331-337.
One of the major cause of recent acute viral hepatitis in Korean adults is hepatitis A virus (HAV) infection. Most of hepatitis A cases are young adults in their twenties... -
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- CD44 Disruption Attenuates Murine Hepatic Ischemia/Reperfusion Injury
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Kim MS, Lee KH, Lee WM, Jun JH, Kim DH
- KMID: 1094264
- J Korean Med Sci.
- 2011 Jul;26(7):919-926.
- doi: 10.3346/jkms.2011.26.7.919
Neutrophil adhesion and migration are critical in hepatic ischemia/reperfusion (I/R) injury. Despite very strong preclinical data, recent clinical trials failed to show a protective effect of anti-adhesion therapy in reperfusion... -
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- Isolation of rice allergenic cDNA clones from a rice cDNA library by immunoscreening with a polyclonal antibody specific to 16 kD rice allergenic protein
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Kim NI, Kim WC, Lee SM, Lee HK, Rhee HI, Choi YS, Jung YH, Cha SH
- KMID: 1029925
- Exp Mol Med.
- 1999 Dec;31(4):185-190.
Clinical cases of type-1 hypersensitive reaction to rice (Oryza sativa) have been reported in western countries as well as in Japan. Among rice proteins, 14-16 kD globulin proteins... -
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- Intrathecal Gabapentin Increases Interleukin-10 Expression and Inhibits Pro-Inflammatory Cytokine in a Rat Model of Neuropathic Pain
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Lee BS, Jun IG, Kim SH, Park JY
- KMID: 1429210
- J Korean Med Sci.
- 2013 Feb;28(2):308-314.
- doi: 10.3346/jkms.2013.28.2.308
We examined the possible anti-inflammatory mechanisms of gabapentin in the attenuation of neuropathic pain and the interaction between the anti-allodynic effects of gabapentin and interleukin-10 (IL-10) expression in a rat... -
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- Constitutive expression of 4-1BB on T cells enhances CD4+ T cell responses
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Kim J, Choi SP, La S, Seo JS, Kim KK, Nam SH, Kwon B
- KMID: 1119332
- Exp Mol Med.
- 2003 Dec;35(6):509-517.
4-1BB, a transmembrane molecule, member of the tumor necrosis factor receptor superfamily, is an important costimulatory molecule in the immune response, plays a key role in the clonal expansion and... -
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- Tissue-specific expression and subcellular localization of ALADIN, the absence of which causes human triple A syndrome
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Cho AR, Yang KJ, Bae Y, Bahk YY, Kim E, Lee H, Kim JK, Park W, Rhim H, Choi SY, Imanaka T, Moon S, Yoon J, Yoon SK
- KMID: 756230
- Exp Mol Med.
- 2009 Jun;41(6):381-386.
- doi: 10.3858/emm.2009.41.6.043
Triple A syndrome is a rare genetic disorder caused by mutations in the achalasia-addisonianism-alacrima syndrome (AAAS) gene which encodes a tryptophan aspartic acid (WD) repeat-containing protein named alacrima-achalasia-adrenal insufficiency neurologic... -
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- Comprehensive clinical and statistical analysis of hemophilia in Korea
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Kim KY, Yang CH, Cho MJ, Lee M
- KMID: 1733436
- J Korean Med Sci.
- 1988 Sep;3(3):107-115.
- doi: 10.3346/jkms.1988.3.3.107
A Total of 498 cases of hemophilia which were reported by sixteen medical centers in Korea were reviewed and analyzed. Hemophilia A comprised 425 cases (85.3%) and the remaining... -
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- Incidence and Seroprevalence of Hepatitis A Virus Infections among Young Korean Soldiers
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Kang CI, Choi CM, Park TS, Lee DJ, Oh MD, Choe KW
- KMID: 1778368
- J Korean Med Sci.
- 2007 Jun;22(3):546-548.
- doi: 10.3346/jkms.2007.22.3.546
This study was performed to determine the incidence and seroprevalence of hepatitis A virus (HAV) infections in young soldiers in the Republic of Korea Army. From January 2000 through December... -
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- The Role of Keratinocyte-derived Chemokine in Hemorrhage-induced Acute Lung Injury in Mice
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Lee BH, Lee TJ, Jung JW, Oh DJ, Choi JC, Shin JW, Park IW, Choi BW, Kim JY
- KMID: 1781993
- J Korean Med Sci.
- 2009 Oct;24(5):775-781.
- doi: 10.3346/jkms.2009.24.5.775
Dominant inflammatory cytokines might be different depending on the underlying causes of acute lung injury (ALI). The role of kertinocyte-derived chemokine (KC), a potent chemoattractant for neutrophils, has not been... -
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- Association of DNA-dependent protein kinase with hypoxia induciblefactor-1 and its implication inresistance to anticancer drugs in hypoxic tum or cells
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Um JH, Kang CD, Bae JH, Shin GG, Kim DW, Kim DW, Chung BS, Kim SH
- KMID: 1097105
- Exp Mol Med.
- 2004 Jun;36(3):233-242.
Tumor hypoxia contributes to the progression of a malignant phenotype and resistance to ionizing radiation and anticancer drug therapy. Many of these effects in hypoxic tumor cells are mediated by... -
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- Clinical features of patients with fulminant hepatitis A requiring emergency liver transplantation: comparison with acute liver failure due to other causes
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Kim JD, Choi JY, Park CH, Song MJ, Jang JW, Bae SH, Yoon SK, Lee YS, You YK, Kim DG
- KMID: 1782217
- Korean J Hepatol.
- 2010 Mar;16(1):19-28.
- doi: 10.3350/kjhep.2010.16.1.19
BACKGROUND/AIMS: According to recent prevalence of hepatitis A virus (HAV) infection, acute liver failure (ALF) due to HAV infection is observed frequently in parallel. The aim of this study was... -
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