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Three Cases of Allopurinol Hypersensitivity Syndrome

Bang HD, Chung JH, Cho KH, Youn JI

  • KMID: 2115947
  • Korean J Dermatol.
  • 1995 Feb;33(1):130-134.
The allopurinol hypersensicivity syndrome is a rare, but life thereaning immunologic reaction of allopurinol therapy, characterized by multiple abnormalities such as fever, rash, decreased renal function, hepatocellular injury, leukocytosis, and...
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The Effect of the Allopurinol on Uric Acid Stone

Koo KS

  • KMID: 1677656
  • Korean J Urol.
  • 1975 Jun;16(2):101-107.
The effectiveness of Allopurinol in the treatment of uric acid stone was evaluated in the Department of Urology, Chung-Ang University Hospital during the period of March, l973 to April, 1974....
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A Case of Allopurinol Hypersensitivity Syndrome

Jeon HJ, Bang HD, Kim KH, Kim KJ

Allopurinol is a xanthine oxidase inhibitor widely used to control plasma uric acid levels. Serious and life threatening adverse effects such as the allopurinol hypersensitivity syndrome(AHS) are rare. We describe...
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Effects of allopurinol on experimentally induced pancreatitis of rats

Lee MH, Hwang SG, Kim SJ

  • KMID: 1857638
  • Korean J Gastroenterol.
  • 1992 Apr;24(2):347-353.
No abstract available.
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5 Cases of Allopurinol Hypersensitivity Syndrome

  • KMID: 2299643
  • Korean J Asthma Allergy Clin Immunol.
  • 2006 Mar;26(1):83-88.
Allopurinol hypersensitivity syndrome is a rare, but life-threatening adverse reaction to allopurinol therapy. Clinically, it is characterized by multiple systemic abnormalities such as fever, rash, decreased renal function, hepa-tocellular injury,...
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Allopurinol Induced Abnormalities of Liver Function Test in Gout Patients

Seo GH, Ahn HJ, Cha HS, Kim JS, Koh KC, Koh EM

  • KMID: 1544928
  • J Korean Rheum Assoc.
  • 1999 Mar;6(1):62-68.
Liver function tests before treatment showed abnormalities of liver function tests during treatment, while 15(68. 2%) of 22 patients who had abnormal liver function tests before treatment showed abnormalities during...
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Successful desensitization for treatment of an exfoliative dermatitis to allopurinol

Park JW, Hong CS, Yun YY, Kim CW, Kim JS, Jung WC, Park JY, Cho YJ, Huh AJ

  • KMID: 2286010
  • J Asthma Allergy Clin Immunol.
  • 1999 Dec;19(6):980-984.
Allopurinol is widely used for chronic tophaceous gout as a uric acid lowering agent. Hypersensitivity to allopurinol occurrs in about 10% of patients, which limits the usage of allopurinol. The...
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THE EFFECTS OF PROSTAGLANDIN E1 AND ALLOPURINOL ON SKIN FLAP SURVIVAL

Kim ES, Rah DK, Tark KC, Park BY

  • KMID: 1530178
  • J Korean Soc Plast Reconstr Surg.
  • 1997 Sep;24(5):893-900.
No abstract available.
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A Case of Allopurinol Hypersensitivity Syndrome

Kim BJ, Kim MN, Ro BI, Song KY

  • KMID: 2303041
  • Korean J Dermatol.
  • 2003 Feb;41(2):251-254.
Allopurinol(4-hydroxypyrazolo[3, 4-d]pyrimidine) is an analog of hypoxanthine, widely used in the treatment of gout and in some patients develop the allopurinol hypersensitivity syndrome. Allopurinol hypersensitivity syndrome is characterized by multiple...
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Two Cases of Allopurinol hypersensitivity syndrome

Park MW, Kim SS, Lee JJ

  • KMID: 2302747
  • Korean J Dermatol.
  • 2005 Jan;43(1):114-117.
Allopurinol hypersensitivity syndrome typically occurs in persons with preexisting renal failure, weeks to months after allopurinol is begun, the patient develops a generalized rash that often evolves to exfoliative erythroderma....
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Effects of verapamil and allopurinol on ischemia-reperfusion injury in rat liver

Lee YH, Cheon JD, Kim JS, Kang G, Pai ST

  • KMID: 1693918
  • J Korean Surg Soc.
  • 1993 Sep;45(3):307-313.
No abstract available.
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Allopurinol hypersensitivity syndrome and pure red cell aplasia associated with allopurinol treatment

Lee JH, Heo JH, Kwon KA, Han DH, Hwang JW, Cho S, Kim SR

  • KMID: 2257336
  • Korean J Med.
  • 2009 Feb;76(2):220-224.
Allopurinol is widely used to reduce serum uric acid levels and, generally, has mild side effects. Rarely, allopurinol hypersensitivity syndrome occurs and this consists of severe systemic skin lesions, fever,...
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Three Cases of Allopurinol-induced DRESS Syndrome

Jeon EK, Lee KM, Kwon YB, Seo YJ, Park JK, Lee JH

  • KMID: 2087389
  • Korean J Dermatol.
  • 2007 Jul;45(7):714-719.
Allopurinol (4-hydroxypyrazolo-[3,4-d]pyrimidine) is an effective and widely used xanthine oxidase inhibitor administered in the treatment of hyperuricemic states such as gout. Allopurinol-induced DRESS (Drug rash with eosinophilia and systemic symptoms)...
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The potential renoprotection of xanthine oxidase inhibitors: Febuxostat versus allopurinol

Ryu DR

No abstract available.
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Treatment of Acquired Perforating Dermatosis in Chronic Renal Failure with Allopurinol

Park HJ, Lee YS

  • KMID: 2302227
  • Korean J Dermatol.
  • 2007 May;45(5):509-511.
The perforating disorder is characterized by transepidermal elimination of altered dermal substances, which comprises Kyrle's disease, perforating folliculitis, elastosis perforans serpiginosa, and reactive perforating collagenosis. The term 'acquired perforating dermatosis'...
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Two Cases of Allopurinol Hypersensitivity Syndrome in Patients Receiving Thiazide Therapy due to Hypertension

Song HJ, Kim CO, Lee KS

  • KMID: 2249390
  • Korean J Dermatol.
  • 2005 Oct;43(10):1426-1429.
Allopurinol hypersensitiviy syndrome (AHS) is a rare immunologic response to allopurinol, characterized by multiple findings such as skin rash, fever, hepatic dysfunction, decreased renal function, leukocytosis and eosinophilia. The risk...
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Two Cases of Allopurinol Hypersensitivity Syndrome due to Use of Allopurinol for the Patient with Asymptomatic Hyperuricemia

Cho WI, Yoon YH, Kim MN, Seo SJ, Hong CK, Ro BI

  • KMID: 2302591
  • Korean J Dermatol.
  • 2005 Jul;43(7):961-964.
Allopurinol (4-hydroxypyrazolo[3, 4-d]pyrimidine) is a xanthine oxidase inhibitor and is widely used in the treatment of hyperuricemia. Allopurinol hypersensitivity syndrome (AHS) includes a prolonged illness initially manifested by fever, a...
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A Case of Allopurinol-Induced Fixed Drug Eruption Confirmed With a Lymphocyte Transformation Test

Kim MH, Shim EJ, Jung JW, Sohn SW, Kang HR

Allopurinol is one of the causative drugs that induce fixed drug eruption (FDE). The lymphocyte transformation test (LTT) is a safe and reliable diagnostic procedure for drug allergy, but is...
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Treatment of Recalcitrant Acquired Reactive Perforating Collagenosis with Low-dose Allopurinol

Shin MS, Lee DR, Park MY

  • KMID: 2248798
  • Korean J Dermatol.
  • 2007 Nov;45(11):1230-1232.
Reactive perforating collagenosis is one of a range of essential perforating disorders and is characterized by the transepithelial elimination of altered collagen. Two types have been recognized: the inherited, or...
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Effect of Allopurinol on Methylmercuric Chloride in Cultured O1igodendrocytes

Park ST, Park BR, Chung YT

To elucidate the neurotoxic mechanism of methylmercury on cultured bovine oligodendrocytes, neurotoxic effect was estimated by MTT assay after cultures were exposed to various concentrations of methylmercuric chloride (MMC). In...
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