- Intermittent Negative Hydrostatic Pressure and Chondrocyte Metabolism
-
Baek GH, Suh JK, Ahn JH
- KMID: 2189686
- J Korean Orthop Assoc.
- 1998 Aug;33(4):1199-1205.
Experimental findings have suggested that the metabolic activities of articular cartilage can be influenced by mechanical stimuli. Our recent mathematical analysis predicted that cyclic compressive loading may create periods of... -
- CITED
-
- Close
- SHARE
-
- Close
- Porous Microcarrier-Enabled Three-Dimensional Culture of Chondrocytes for Cartilage Engineering: A Feasibility Study
-
Jin GZ, Kim HW
- KMID: 2361007
- Tissue Eng Regen Med.
- 2016 Jun;13(3):235-241.
- doi: 10.1007/s13770-016-0038-6
Cartilage repair is substantially intractable due to poor self-healing ability. Porous microspheres can be a fascinating three-dimensional matrix for cell culture and injectable carrier in cartilage engineering. In this study,... -
- CITED
-
- Close
- SHARE
-
- Close
- The Expression of Extracellular Matrix mRNA in the Chondrocytes of the Femoral Head Affected by Avascular Necrosis
-
Chung WY, Lee WS, Kim SB, Bae IT, Park WK
- KMID: 2162618
- J Korean Hip Soc.
- 2008 Dec;20(4):320-325.
- doi: 10.5371/jkhs.2008.20.4.320
PURPOSE: The aim of this study was to evaluate the expression of type II collagen, aggrecan, VEGF-A and PEDF mRNAs in the human chondrocytes derived from the articular cartilage of... -
- CITED
-
- Close
- SHARE
-
- Close
- Identification of a novel heterozygous mutation of ACAN in a Korean family with proportionate short stature
-
Kim YM, Cheon CK, Lim HH, Yoo HW
- KMID: 2435950
- J Genet Med.
- 2018 Dec;15(2):102-106.
- doi: 10.5734/JGM.2018.15.2.102
Aggrecan is a proteoglycan in the extracellular matrix of growth plate and cartilaginous tissues. Aggrecanopathy has been reported as a genetic cause not only for severe skeletal dysplasia but also... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Type I Collagen Concentration in Hydrogel on the Growth and Phenotypic Expression of Rat Chondrocytes
-
Jin GZ, Kim HW
- KMID: 2394972
- Tissue Eng Regen Med.
- 2017 Aug;14(4):383-391.
- doi: 10.1007/s13770-017-0060-3
It is controversial whether type I collagen itself can maintain and improve chondrogenic phenotype of chondrocytes in a three-dimensional (3D) environment. In this study, we examined the effect of type... -
- CITED
-
- Close
- SHARE
-
- Close
- Change of the Effect of TGF-beta1 on Physeal Chondrocytes According to Culture Methods in Vitro
-
Kim BS, Jahng JS
- KMID: 2189415
- J Korean Orthop Assoc.
- 1999 Oct;34(5):849-857.
PURPOSE: We intended to check the growth rates and phenotypic markers of chondrocytes in the dedifferentiated cells cultivated in various conditions in order to establish the ideal culture system for... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Three Dimensional Culture Using Alginate-Fibrin Beads on the Chondrogenic Differentiation of Rabbit's Perichondrial Cells
-
Yoo WJ, Choi IH, Chung CY, Cho TJ, Lee CH
- KMID: 2023930
- J Korean Orthop Res Soc.
- 2003 Apr;6(1):1-6.
PURPOSE: To evaluate the usefulness of three dimensional culture using alginate-fibrin beads on the chondrogenic differentiation of rabbit's perichondrial cells. MATERIALS AND METHODS: Rib perichondrial cells from rabbit expanded by... -
- CITED
-
- Close
- SHARE
-
- Close
- Osteogenic Gene Expression on Anodizing Titanium Surface
-
Kim W, Kim YS, Jeon S, Jun S, Lee E, Jang H, Kwon J, Rim J
- KMID: 1434420
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2012 Mar;34(2):91-99.
PURPOSE: The purpose of this study was to evaluate the expression of osteogenic genes associated with bone regeneration on anodizing titanium surface. METHODS: 20x20x1 (mm) commercially pure titanium plate was made,... -
- CITED
-
- Close
- SHARE
-
- Close
- Resveratrol Has Anabolic Effects on Disc Degeneration in a Rabbit Model
-
Kwon YJ
- KMID: 2158045
- J Korean Med Sci.
- 2013 Jun;28(6):939-945.
- doi: 10.3346/jkms.2013.28.6.939
This study was done to evaluate whether injections of resveratrol, a natural compound found in the skin of grapes, had anabolic effects on degenerated intervertebral discs in a rabbit model.... -
- CITED
-
- Close
- SHARE
-
- Close
- A Minimally Invasive Rabbit Model of Progressive and Reproducible Disc Degeneration Confirmed by Radiology, Gene Expression, and Histology
-
Kwon YJ
- KMID: 2190818
- J Korean Neurosurg Soc.
- 2013 Jun;53(6):323-330.
- doi: 10.3340/jkns.2013.53.6.323
OBJECTIVE: To develop a simple, reproducible model of disc degeneration in rabbits through percutaneous annular puncture and to confirm the degree of degeneration over time. METHODS: Fifteen New Zealand white rabbits... -
- CITED
-
- Close
- SHARE
-
- Close
- Influence of synovial Joint Fluid of Rheumatic and Osteoarthritic on Chondrocyte in vitro
-
Sung JH, Ryu JD, Kim YH, Jung KS, Kim WY, Hwang HJ, Kim JY
- KMID: 2199146
- J Korean Orthop Res Soc.
- 2000 Apr;3(1):5-13.
PURPOSE: Earlier work suggested that two cytokines inhibit synthesis of type II collagen and of aggrecans by chondrocytes and they depress chondrocyte proliferation, but there was little report how the... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Trichostatin A on the Chondrogenesis from Human Mesenchymal Stem Cells
-
Lee J, Im GI
- KMID: 2394974
- Tissue Eng Regen Med.
- 2017 Aug;14(4):403-410.
- doi: 10.1007/s13770-017-0041-6
Histone deacetylase inhibitors (HDACi) are a class of compounds that suppress the function of histone deacetylases (HDACs). This study was performed to examine the effects of Trichostatin A (TSA), a... -
- CITED
-
- Close
- SHARE
-
- Close
- Multipotentiality of CD34- Cells Extracted from Human Cord Blood
-
Kim SH, Yang IH, Kim HO, Lee JW
- KMID: 2399083
- J Korean Orthop Assoc.
- 2004 Jun;39(3):315-322.
PURPOSE: We evaluated the differentiation potential of CD34-cells expanded from human cord blood into several differentiated cells, namely, osteoblasts, chondrocytes and adipocytes. MATERIALS AND METHODS: CD34- cells, extracted from cord... -
- CITED
-
- Close
- SHARE
-
- Close
- Different Expression of Extracellular Matrix Genes: Primary vs. Recurrent Disc Herniation
-
Kuh SU, Kwon YM, Chin DK, Kim KS, Jin BH, Cho YE
- KMID: 1495085
- J Korean Neurosurg Soc.
- 2010 Jan;47(1):26-29.
- doi: 10.3340/jkns.2010.47.1.26
OBJECTIVE: Recurrent lumbar disc herniation has been reported to occur in 5% to 15% of surgically treated primary lumbar disc herniation cases. We investigated the molecular biologic characteristics of primary... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of CoCl2 on multi-lineage differentiation of C3H/10T1/2 mesenchymal stem cells
-
Yoo HI, Moon YH, Kim MS
- KMID: 2150473
- Korean J Physiol Pharmacol.
- 2016 Jan;20(1):53-62.
- doi: 10.4196/kjpp.2016.20.1.53
Mesenchymal stem cells (MSCs) in the bone marrow and other somatic tissues reside in an environment with relative low oxygen tension. Cobalt chloride (CoCl2) can mimic hypoxic conditions through transcriptional... -
- CITED
-
- Close
- SHARE
-
- Close
- Alginate-Hyaluronic Acid-Collagen Composite Hydrogel Favorable for the Culture of Chondrocytes and Their Phenotype Maintenance
-
Mahapatra , Jin GZ, Kim HW
- KMID: 2360802
- Tissue Eng Regen Med.
- 2016 Oct;13(5):538-546.
- doi: 10.1007/s13770-016-0059-1
Articular cartilage has limited regeneration capacity, thus significant challenge has been made to restore the functions. The development of hydrogels that can encapsulate and multiply cells, and then effectively maintain... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of Chicken Cartilage Derived Matrix Protein 10 (CCMP 10) in Chondrogenesis
-
Oh KY, Kim HJ, Kim SM, Park JC
- KMID: 1517158
- Korean J Phys Anthropol.
- 2003 Mar;16(1):15-25.
Over the past few years, considerable progress has been achieved about the extracellular elements and intracellular regulatory molecules that are involved in the regulation of chondrogenesis. However, little is known... -
- CITED
-
- Close
- SHARE
-
- Close
- Regulation of aggrecanase-1 and aggrecanase-2 expressions by hypoxia and cytokines in rheumatoid fibroblast-like synoviocytes
-
Kim HJ, Bae EK, Kim J, Chai JY, Jeon CH, Cha HS, Ahn KS, Koh EM
- KMID: 2256622
- Korean J Med.
- 2006 Aug;71(2):182-188.
BACKGROUND: While aggrecanases (aggrecanase-1 and aggrecanase-2) are substantially responsible for cartilage aggrecan breakdown in rheumatoid arthritis (RA), not much information is available on the regulation or expression of the two... -
- CITED
-
- Close
- SHARE
-
- Close
- Establishment of Human Bone Marrow-Derived Mesenchymal Stem Cell Lines with SV40 Large T Antigen and Their Differentiation to Chondrocytes
-
Park JA, Kim EK, Koh SH, Kang HJ, Shin HY, Ahn HS
- KMID: 2278338
- Korean J Pediatr Hematol Oncol.
- 2005 Apr;12(1):99-107.
PURPOSE: Mesenchymal stem cells (MSC) can be isolated from bone marrow (BM) and when systemically administrated to different species, they undergo site-specific differentiation. In this study, we isolated MSC from... -
- CITED
-
- Close
- SHARE
-
- Close
- Transforming Growth Factor-beta1 and Bone Morphogenetic Protein-2 Upregulates Matrix Synthesis and Chondrogenic Phenotype in Intervertebral Disc Cells
-
Kim DJ, Moon SH, Kim H, Kwon EH, Hahn SB, Cheon YM, Kim HS, Han KJ, Park MS, Lee HM
- KMID: 2003220
- J Korean Soc Spine Surg.
- 2002 Sep;9(3):165-171.
- doi: 10.4184/jkss.2002.9.3.165
OBJECTIVES: To determine effect of transforming growth factor-beta1 and bone morphogenetic protein-2 in matrix synthesis and expression of chondrogenic phenotype in human intervertebral disc cells. MATERIALS AND METHODS: The intervertebral disc... -
- CITED
-
- Close
- SHARE
-
- Close
