- Effect of Adenine on Clozapine-induced Neutropenia in Patients with Schizophrenia: A Preliminary Study
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Takeuchi I, Kishi T, Hanya M, Uno J, Fujita K, Kamei H
- KMID: 2171046
- Clin Psychopharmacol Neurosci.
- 2015 Aug;13(2):157-162.
- doi: 10.9758/cpn.2015.13.2.157
OBJECTIVE: This study examined the utility of adenine for preventing clozapine-induced neutropenia. METHODS: This retrospective study examined the effect of adenine on clozapine-induced neutropenia in patients with treatment-resistant schizophrenia and was... -
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- Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies
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Tomita T, Goto H, Sumiya K, Yoshida T, Tanaka K, Kohda Y
- KMID: 2356166
- Clin Psychopharmacol Neurosci.
- 2016 Nov;14(4):391-395.
- doi: 10.9758/cpn.2016.14.4.391
Because adenine is effective for managing cases of radiation-induced and drug-induced leukopenia, it may be effective in cases of antipsychotic-induced leukopenia and neutropenia. Here, we report our experience with patients... -
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- Dihydroxyadenine crystal-induced nephropathy presenting with rapidly progressive renal failure
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Verma R, Niraimathi M, Prasad P, Agrawal V
- KMID: 2447168
- Kidney Res Clin Pract.
- 2018 Sep;37(3):287-291.
- doi: 10.23876/j.krcp.2018.37.3.287
Adenine phosphoribosyltransferase enzyme deficiency is a rare, autosomal recessive disorder. It is a disease limited to the renal system and usually presents with urolithiasis. Herein, we report a young female... -
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- Recent trends in two-photon auto-fluorescence lifetime imaging (2P-FLIM) and its biomedical applications
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Ranawat H, Pal S, Mazumder N
- KMID: 2470025
- Biomed Eng Lett.
- 2019 Aug;9(3):293-310.
- doi: 10.1007/s13534-019-00119-7
Two photon fluorescence microscopy and the numerous technical advances to it have served as valuable tools in biomedical research. The fluorophores (exogenous or endogenous) absorb light and emit lower energy... -
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- Adenine attenuates lipopolysaccharide-induced inflammatory reactions
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Silwal P, Lim K, Heo JY, Park JI, Namgung U, Park SK
- KMID: 2414262
- Korean J Physiol Pharmacol.
- 2018 Jul;22(4):379-389.
- doi: 10.4196/kjpp.2018.22.4.379
A nucleobase adenine is a fundamental component of nucleic acids and adenine nucleotides. Various biological roles of adenine have been discovered. It is not produced from degradation of adenine nucleotides... -
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- Effects of Homogentisic Acid and Natural Products Derived from Pinellia ternata on Secretion, Production and Gene Expression of MUC5AC Mucin from Cultured Airway Epithelial Cells
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Lee HJ, Lee CJ
- KMID: 2376496
- Nat Prod Sci.
- 2017 Mar;23(1):29-34.
- doi: 10.20307/nps.2017.23.1.29
In this study, we investigated whether adenosine, adenine, uridine and homogentisic acid derived from Pinellia ternata affect the secretion, production and gene expression of MUC5AC mucin from airway epithelial cells.... -
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- A Mitochondrial Mutation in Leber's Hereditary Optic Neuropathy
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Hwang JM, Park HW
- KMID: 2205183
- J Korean Ophthalmol Soc.
- 1995 Dec;36(12):2218-2224.
Leber's hereditary optic neuropathy is caused by a single nucleotide change in the mitochondrial deoxynucleic acid(mtDNA). We identified a single guanine to adenine transition mutation in the mitochondrial DNA at... -
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- SLC26A4 Mutations in Korean Population
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Kim BG
- KMID: 1963750
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2014 Nov;57(11):733-737.
- doi: 10.3342/kjorl-hns.2014.57.11.733
SLC26A4 mutations are common cause of congenital hearing loss in East Asia. The carrier frequency of SLC26A4 mutations is 1 in 75 in Korean populations. The SLC26A4 mutation spectrum varies... -
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- Is tenofovir disoproxil fumarate an all-powerful weapon in the treatment of chronic hepatitis B?
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Kim JH, Lee JS
- KMID: 2129658
- Korean J Intern Med.
- 2015 Jan;30(1):23-26.
- doi: 10.3904/kjim.2015.30.1.23
No abstract available. -
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- A Case of Leber's Hereditary Optic Nouropathy Showing 11778 Point Mutation of Mitochondrial DNA
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Jung YS, Park SK, Lee SY, Hah JS, Park MY, Lee SJ, Lee J
- KMID: 1969409
- Yeungnam Univ J Med.
- 1999 Jun;16(1):114-118.
- doi: 10.12701/yujm.1999.16.1.114
Leber's hereditary optic neuropathy(LHON) is an optic nerve disease that causes blindness and is associated with maternally inherited mitochondrial DNA(mt DNA) mutations. The most common mitochondrial DNA mutation among LHON... -
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- Adenine Nucleotide Translocator as a Regulator of Mitochondrial Function: Implication in the Pathogenesis of Metabolic Syndrome
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Kim EH, Koh EH, Park JY, Lee KU
- KMID: 2222369
- Korean Diabetes J.
- 2010 Jun;34(3):146-153.
- doi: 10.4093/kdj.2010.34.3.146
Mitochondria play key roles in energy production and intracellular reactive oxygen species (ROS) generation. Lines of evidence have shown that mitochondrial dysfunction contributes to the development of metabolic syndrome. The... -
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- Isolation and Structure Determination of an Imidazo-pyrimidine, 5-Chlorocavernicolin, Maleimide oximes and Nucleosides from a Marine Sponge Extract
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Kulkarni R, Kim JH, Kim YH, Oh S, Na M
- KMID: 2409595
- Nat Prod Sci.
- 2015 Mar;21(1):25-29.
- doi: 10.0000/nps.2015.21.1.25
In a continuation of our studies to discover bioactive secondary metabolites from marine sources, we further investigated samples from a tryptamine and phenyl-alkane producing sponge, which resulted in the isolation... -
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- MELAS Syndrome Confirmed by Mitochondrial DNA Analysis in Siblings
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Rah YG, Chae SA, Lim IS, Lee DK, Yoo BH, Ko TS, Yoo HW
- KMID: 1946343
- J Korean Pediatr Soc.
- 1999 Mar;42(3):412-418.
MELAS(mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) syndrome is a major subgroup of mitochondrial myopathy. Recent advances in molecular genetics revealed specific mutations in mitochondrial DNA which cause MELAS.... -
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- Effect of Phototherapy on the Riboflavin Status in Neonatal Hyperbilirubinemia
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Bang YO
- KMID: 1699480
- J Korean Pediatr Soc.
- 1982 May;25(5):436-444.
Riboflavin in unstable in light and has a maximum absorption at 450nm. A study was designed to determine whether riboflavin deficiency developed in neonate who received phototherapy with eight day... -
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- Chemical Constituents of the Fruiting Bodies of Clitocybe nebularis and Their Antifungal Activity
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Kim YS, Lee IK, Seok SJ, Yun BS
- KMID: 2411406
- Mycobiology.
- 2008 Jun;36(2):110-113.
During a continuing search for antimicrobial substances from Korean native wild mushroom extracts, we found that the methanolic extract of the fruiting body of Clitocybe nebularis exhibited mild antifungal activity... -
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- In vitro Effects of Plant Extracts, and Phytohormones on Mycelial Growth of Anthracnose Fungi
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Alam S, Han KD, Lee JM, Hur H, Shim JO, Chang KC, Lee TS, Lee MW
- KMID: 2312438
- Mycobiology.
- 2004 Sep;32(3):134-138.
Water extracts of six plants, such as Allium sativum, A. cepa, Zingiber officinale, Platycodon grandiflorum, Oenanthe javanica, and Capsella brusapastoris, were tested in vitro for inhibitory activity against mycelial growth... -
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- Changes of the Erythrocyte Glutathione Reduetase Activity before nd after Anestbesia
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Lee YJ, Lee CH
- KMID: 2090342
- Korean J Anesthesiol.
- 1977 Jun;10(1):29-35.
Riboflavin is a constituent of coenzyme, FMN, FAD and its content varies according to the physiological and nutritional status. However, the measurement of its content is so disputable that a... -
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- Effects of Adenosine 5'-Tetraphosphate on the Cardiac Activity*
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Lee JW, Park KS, Kong ID
- KMID: 2093590
- Korean Circ J.
- 1996 Jun;26(3):704-712.
- doi: 10.4070/kcj.1996.26.3.704
BACKGROUND: Adenosine 5'-tetraphosphate(ATPP), an endogenous nucleotide, is stored in cells and released into the extracellular space upon stimulation. Some of the biological responses to ATPP were reported, but characteristics of... -
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- Phenotypic Changes of Intermediate Filament Proteins during Degeneration and Regeneration of Rat Leg Muscles following Physical Injury
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Kim HS, Yoo KS, Kim BH, Sohn SK
- KMID: 2189382
- J Korean Orthop Assoc.
- 2001 Dec;36(6):613-621.
PURPOSE: The aim of this experiment was to observe the phenotypic changes of intermediate filaments in skeletal muscle fibers during the degeneration and regeneration of the physical injury. MATERIALS AND... -
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- A Case of Focal Acantholytic Dyskeratosis Presenting as a Solitary Papule
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Park SJ, Kim JY, Yi JA, Lee WJ
- KMID: 2302918
- Korean J Dermatol.
- 2004 Mar;42(3):317-319.
Focal acantholytic dyskeratosis (FAD) was introduced by Ackerman to describe a group of clinically various dermatologic conditions having a similar histologic appearance. The characteristic histologic findings included (1) suprabasilar clefts... -
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