- Recent advance in primary immune deficiency disorders
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Kang HJ, Shin HY, Ahn HS
- KMID: 2281068
- Korean J Pediatr.
- 2009 Jun;52(6):649-654.
- doi: 10.3345/kjp.2009.52.6.649
The immune system is comprised of cells and molecules whose collective and coordinated response to the introduction of foreign substance is referred to as the immune response. Defense against microbes... -
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- Innate Immunity and Organ Transplantation
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Yang CW
- KMID: 1512740
- Hanyang Med Rev.
- 2006 Aug;26(3):48-53.
The immune response of transplanted grafts has been considered to be within the realm of the adaptive immune system. Recently, with the discovery of the Toll-like receptors (TLRs), the role... -
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- Innate immunity in asthma
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Kim HY
- KMID: 1803537
- Allergy Asthma Respir Dis.
- 2014 Nov;2(5):317-325.
- doi: 10.4168/aard.2014.2.5.317
Asthma is a complex and heterogeneous disease with several phenotypes. Most studies have focused on allergic asthma associated with allergen sensitization and adaptive immunity. On the other hand, nonallergic asthma... -
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- The Role of Epithelium in the Pathophysiology of Chronic Rhinosinusitis : An Update
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Min JY, Dhong HJ
- KMID: 2297560
- J Rhinol.
- 2013 May;20(1):14-19.
Chronic rhinosinusitis (CRS) is characterized by persistent symptomatic inflammation of the nasal and paranasal sinus mucosa resulting from the interaction of multiple host and environmental factors. Although the etiology of... -
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- Regulation of Innate Immunity via MHC Class II-mediated Signaling; Non-classical Role of MHC Class II in Innate Immunity
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Park HL, Nam JH
- KMID: 1449896
- J Bacteriol Virol.
- 2011 Sep;41(3):205-207.
- doi: 10.4167/jbv.2011.41.3.205
MHC class II has long been known to play a classical role in antigen presentation and to act as a signal transducer capable of inducing the adaptive immunity needed to... -
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- Vitamin D and Allergic Disease
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Cho JH
- KMID: 2132120
- J Rhinol.
- 2014 Nov;21(2):92-95.
- doi: 10.0000/jr.2014.21.2.92
Recently, the role of vitamin D in immunomodulation has been studied and shown to be significantly associated with immune function. A causal relationship exists between vitamin D and innate and... -
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- Inflammasomes in antiviral immunity: clues for influenza vaccine development
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Yamazaki T, Ichinohe T
- KMID: 2049091
- Clin Exp Vaccine Res.
- 2014 Jan;3(1):5-11.
- doi: 10.7774/cevr.2014.3.1.5
Inflammasomes are cytosolic multiprotein complexes that sense microbial motifs or cellular stress and stimulate caspase-1-dependent cytokine secretion and cell death. Recently, it has become increasingly evident that both DNA and... -
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- Cloning of Danio rerio toll-like receptor 1
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Choi HY
- KMID: 2036973
- Korean Lepr Bull.
- 2005 Dec;38(2):3-14.
Toll-like receptors (TLRs) play a central role of innate immunity as well as of enhancing the adaptive immunity. TLR1 interacts with TLR2 to recognize the mycobacterial 19-kD lipoprotein. Danio rerio... -
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- The Innate Immune Responses in Pathogenesis of Chronic Rhinosinusitis
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Mo JH
- KMID: 2146667
- J Rhinol.
- 2014 May;21(1):22-27.
- doi: 10.0000/jr.2014.21.1.22
Chronic rhinosinusitis (CRS) is a multifactorial and heterogeneous disease, and variousfactors, such as inflammation, infection, fungus, and superantigens, have been proposed to play crucial roles in its pathogenesis. Recently, the... -
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- Immunologic Role of Fungi in the Pathophysiology of Chronic Rhinosinusitis
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Shin SH
- KMID: 2132084
- J Rhinol.
- 2013 Nov;20(2):82-87.
Chronic rhinosinusitis (CRS) is a very common condition but it's pathogenesis is not completely understood. Although, fungi have been suggested to play an important role in the pathogenesis of CRS,... -
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- Immunology of Cutaneous Mycoses
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Chung HJ, Lee KH
- KMID: 1907710
- Hanyang Med Rev.
- 2006 Nov;26(4):34-43.
Recently, the relevance of fungal infection has increased enormously, because of the increasing incidence of HIV infection, organ transplantation, and neoplastic disorders. A variety of underlying conditions, including impaired immune... -
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- Prophylactic and Therapeutic Modulation of Innate and Adaptive Immunity Against Mucosal Infection of Herpes Simplex Virus
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Uyangaa E, Patil AM, Eo SK
- KMID: 2150807
- Immune Netw.
- 2014 Aug;14(4):187-200.
- doi: 10.4110/in.2014.14.4.187
Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) are the most common cause of genital ulceration in humans worldwide. Typically, HSV-1 and 2 infections via mucosal route result... -
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- The Role of Toll-Like Receptor in Organ Transplantation
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Chung BH, Yang CW
- KMID: 2201869
- J Korean Soc Transplant.
- 2007 Dec;21(2):181-187.
The immune response of transplanted grafts has been considered to be within the realm of the adaptive immune system. Recently, with the discovery of the Toll-like receptors (TLRs), the role... -
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- Pathogenic Role of Autophagy in Rheumatic Diseases
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Choi YJ, Yoo WH
- KMID: 2352464
- J Rheum Dis.
- 2016 Aug;23(4):202-211.
- doi: 10.4078/jrd.2016.23.4.202
Autophagy is a principle catabolic process mediated by lysosomes in eukaryotic cells. This is an intracellular homeostatic mechanism crucial for degradation in acidic lysosomal compartments of waste components from the... -
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- Regulation of Intestinal Homeostasis by Innate Immune Cells
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Kayama H, Nishimura , Takeda K
- KMID: 2150782
- Immune Netw.
- 2013 Dec;13(6):227-234.
- doi: 10.4110/in.2013.13.6.227
The intestinal immune system has an ability to distinguish between the microbiota and pathogenic bacteria, and then activate pro-inflammatory pathways against pathogens for host defense while remaining unresponsive to the... -
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- Activation of Innate Immune System During Viral Infection: Role of Pattern-recognition Receptors (PRRs) in Viral Infection
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Jun EJ, Kim YK
- KMID: 1474157
- J Bacteriol Virol.
- 2009 Sep;39(3):145-157.
- doi: 10.4167/jbv.2009.39.3.145
Innate immunity and adaptive immunity are two major immune responses against pathogens. Innate immunity is responsible for the immediate immune response to pathogens. Pattern-recognition receptors (PRRs) play an important role... -
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- Comparison of humoral and cell-mediated immunity in three different C57BL/6N mouse substrains
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Kim HR, Choi JY, Kim KS, Jung YS, Cho JY, Hwang DY, Song HK
- KMID: 2407427
- Lab Anim Res.
- 2017 Jun;33(2):132-139.
- doi: 10.5625/lar.2017.33.2.132
Adaptive immunity is a type of immune response mediated by T and B cells, and is important response for immune response amplification and memory. In this study, the adaptive immunologic... -
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- The Emerging Role of Natural Killer Cells in Innate and Adaptive Immunity
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Kim EM, Ko CB, Myung PK, Cho D, Choi I, Kang HS
- KMID: 1515487
- Immune Netw.
- 2004 Dec;4(4):205-215.
- doi: 10.4110/in.2004.4.4.205
In the early host defense system, effector function of natural killer (NK) cells results in natural killing against target cells such as microbe-infected, malignant, and certain allogenic cells without prior... -
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- Aging and the Immune System: the Impact of Immunosenescence on Viral Infection, Immunity and Vaccine Immunogenicity
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Oh SJ, Lee JK, Shin OS
- KMID: 2466607
- Immune Netw.
- 2019 Dec;19(6):e37.
- doi: 10.4110/in.2019.19.e37
Immunosenescence is characterized by a progressive deterioration of the immune system associated with aging. Multiple components of both innate and adaptive immune systems experience aging-related changes, such as alterations in... -
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- Mucosal vaccine adjuvants update
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Rhee JH, Lee SE, Kim SY
- KMID: 2278788
- Clin Exp Vaccine Res.
- 2012 Jul;1(1):50-63.
- doi: 10.7774/cevr.2012.1.1.50
Mucosal vaccination, capable of inducing protective immune responses both in the mucosal and systemic immune compartments, has many advantages and is regarded as a blue ocean in the vaccine industry.... -
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