- Regulation of acetyl CoA carboxylase mRNA in rat liver by high carbohydrate diet and insulin
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Choi DH, Choi JH, Whang SK, Kim YS
- KMID: 1097014
- Yonsei Med J.
- 1989 Sep;30(3):235-245.
- doi: 10.3349/ymj.1989.30.3.235
Acetyl CoA carboxylase contents in liver cytosol of rats refed a high carbohydrate diet or injected with insulin were measured by an immunoassay method in order to evaluate the... -
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- Effects of medicinal herb water extracts on expression of hepatic glucokinase, pyruvate dehydrogenase and acetyl-CoA carboxylase mRNA
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Kim HS, Kim TW, Kim DJ, Lee JS, Choe M
- KMID: 2269389
- Korean J Nutr.
- 2013 Apr;46(2):119-125.
- doi: 10.4163/kjn.2013.46.2.119
We studied the anti-diabetic effects of medicinal herb water extracts on expression of hepatic glucokinase (GCK), pyruvate dehydrogenase (PDH), and acetyl-CoA carboxylase (ACC) mRNA. The medicinal herbs used for experiments... -
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- Rapid increase of cytosolic content of acetyl-CoA carboxylase isoforms in H9c2 cells by short-term treatment with insulin and okadaic acid
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Park CE, Ko SM, Kim JM, Yoon MY, Kim JY, Kang IS, Kim SS, Ha JH
- KMID: 754991
- Exp Mol Med.
- 1998 Jun;30(2):73-79.
Mammalian acetyl-CoA carboxylase (ACC) is present in two isoforms, alpha and beta, both of which catalyze formation of malonyl-CoA by fixing CO2 into acetyl-CoA. ACC-alpha is highly expressed in lipogenic tissues whereas... -
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- ¹H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses
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Kim J, Oh J, Yoon DH, Sung GH
- KMID: 2470147
- Mycobiology.
- 2019 Sep;47(3):346-349.
- doi: 10.1080/12298093.2019.1625854
AMP-activated protein kinase sucrose non-fermenting 1 (Snf1) is a representative regulator of energy status that maintains cellular energy homeostasis. In addition, Snf1 is involved in the mediation of environmental stress... -
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- Clinical Characteristics of Patients after Aryloxyphenoxy Propionate Herbicide Ingestion
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Lim J, Moon J, Chun B
- KMID: 2368180
- J Korean Soc Clin Toxicol.
- 2016 Dec;14(2):71-77.
- doi: 10.22537/jksct.2016.14.2.71
PURPOSE: No studies have been conducted to investigate the acute toxicity of aryloxyphenoxypropionate herbicides in humans following ingestion. Therefore, this study was conducted to investigate the clinical characteristics of aryloxyphenoxypropionate... -
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- Hypothalamic AMPK Activity in Diabetic Rats
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Namkoong C, Kim MS, Lee WJ, Jang PG, Han SM, Koh EH, Park JY, Lee KU
- KMID: 2008175
- J Korean Diabetes Assoc.
- 2004 Dec;28(6):468-477.
BACKGROUND: AMP-activated protein kinase (AMPK) acts as a cellular energy sensor that is activated during states of low energy charge and it regulates the various metabolic pathways to reestablish the... -
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- Medium- and long-chain triglyceride propofol reduces the activity of acetyl-coenzyme A carboxylase in hepatic lipid metabolism in HepG2 and Huh7 cells
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Wang LY, Wu J, Gao YF, Lin DM, Ma J
- KMID: 2466566
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):19-26.
- doi: 10.4196/kjpp.2020.24.1.19
Medium- and long-chain triglyceride (MCT/LCT) propofol is widely used as an intravenous anesthetic, especially in the intensive care unit. The present study aimed to assess whether MCT/LCT propofol is safe... -
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- Losartan Inhibits Vascular Smooth Muscle Cell Proliferation through Activation of AMP-Activated Protein Kinase
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Kim JE, Choi HC
- KMID: 2071697
- Korean J Physiol Pharmacol.
- 2010 Oct;14(5):299-304.
- doi: 10.4196/kjpp.2010.14.5.299
Losartan is a selective angiotensin II (Ang II) type 1 (AT1) receptor antagonist which inhibits vascular smooth muscle cells (VSMCs) contraction and proliferation. We hypothesized that losartan may prevent cell... -
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- Increase in Fatty Acid Oxidation by AICAR: the Role of p38 MAPK
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Lee WJ, Kim JY, Bae SJ, Koh EH, Han SM, Park HS, Kim HS, Kim MS, Park JY, Lee KU
- KMID: 2177800
- J Korean Diabetes Assoc.
- 2005 Jan;29(1):15-21.
BACKGROUND: AMPK is an enzyme that increases glucose transport and fatty acid oxidation in skeletal muscle. The activation of AMPK stimulates fatty acid oxidation by decreasing the acetyl CoA carboxylase... -
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- Effects of lovastatin on free fatty acid oxidation in human skeletal muscle cells
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Kim DL, Song KH, Kim SK, Kim HR, Ciaraldi T, Henry RR
- KMID: 2081277
- Korean J Med.
- 2007 Jun;72(6):600-606.
BACKGROUDN: Recent clinical studies have suggested that statins improve insulin resistance and glucose metabolism in the skeletal muscle of diabetic patients. To evaluate a possible component of this action, we... -
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- Identification of AMPK activator from twelve pure compounds isolated from Aralia Taibaiensis: implication in antihyperglycemic and hypolipidemic activities
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Li Y, Park J, Wu Y, Cui J, Jia N, Xi M, Wen A
- KMID: 2376955
- Korean J Physiol Pharmacol.
- 2017 May;21(3):279-286.
- doi: 10.4196/kjpp.2017.21.3.279
The root bark extract of Aralia taibaiensis is used traditionally for the treatment of diabetes mellitus in China. The total saponin extracted from Aralia Taibaiensis (sAT) has effective combined antihyperglycemic... -
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- Acetyl-CoA carboxylase beta expression mediated by MyoD and muscle regulatory factor 4 is differentially affected by retinoic acid receptor and retinoid X receptor
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Kim JY, Lee JJ, Kim KS
- KMID: 1088654
- Exp Mol Med.
- 2003 Feb;35(1):23-29.
Mammals have two major isoforms of acetyl-CoA carboxyase (ACC). The 275 kDa beta-form (ACC beta) is predominantly in heart and skeletal muscle while the 265 kDa alpha-form (ACC alpha) is... -
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- Hypoglycemic effect of Rehmannie Radix Preparata (Sookjihwang) extract in streptozotocin-induced diabetic rats
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Kang SJ, Bao CL, Park S, Kim AJ
- KMID: 2313478
- Nutr Res Pract.
- 2010 Oct;4(5):438-442.
Rhemannie Radix Preparata (RRP) has been previously employed in traditional oriental medicine as a treatment for diabetic thirst and improving blood flow. The aim of this study was to evaluate... -
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- The effects of black garlic (Allium satvium) extracts on lipid metabolism in rats fed a high fat diet
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Ha AW, Ying T, Kim WK
- KMID: 2313806
- Nutr Res Pract.
- 2015 Feb;9(1):30-36.
- doi: 10.4162/nrp.2015.9.1.30
BACKGROUD/OBEJECTIVES: The mechanism of how black garlic effects lipid metabolism remains unsolved. Therefore, the objectives of this study were to determine the effects of black garlic on lipid profiles and... -
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- The effect of fucoxanthin rich power on the lipid metabolism in rats with a high fat diet
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Ha AW, Kim WK
- KMID: 2313682
- Nutr Res Pract.
- 2013 Aug;7(4):287-293.
This study determined the effects of fucoxanthin on gene expressions related to lipid metabolism in rats with a high-fat diet. Rats were fed with normal fat diet (NF, 7% fat)... -
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- Grape seed extract (Vitis vinifera) partially reverses high fat diet-induced obesity in C57BL/6J mice
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Park SH, Park TS, Cha YS
- KMID: 2139196
- Nutr Res Pract.
- 2008 Dec;2(4):227-233.
- doi: 10.4162/nrp.2008.2.4.227
The aim of the present study was to assess the anti-obesity effects of grape seed extract (GSE) supplement in C57BL/6J mice. Thirty mice were divided into three groups; normal diet... -
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- Mechanical Stretch-Induced Protection against Myocardial Ischemia-Reperfusion Injury Involves AMP-Activated Protein Kinase
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Hao J, Kim HS, Choi W, Ha TS, Ahn HY, Kim CH
- KMID: 1457694
- Korean J Physiol Pharmacol.
- 2010 Feb;14(1):1-9.
- doi: 10.4196/kjpp.2010.14.1.1
AMP-activated protein kinase (AMPK) protects various tissues and cells from ischemic insults and is activated by many stimuli including mechanical stretch. Therefore, this study investigated if the activation of AMPK... -
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- The Effect of Zoledronate on the Differentiation of Human Amniotic Fluid-Derived Mesencymal Stem Cells into Adipocytes
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Joo BS, An JH, An BM, Choi TY, Song DY, Kim HH, Moon HS
- KMID: 2300065
- Korean J Blood Transfus.
- 2008 Dec;19(3):231-238.
BACKGROUND: Amniotic fluid is a rich source of fetal mesenchymal stem cells (MSCs). However, little is known about whether bisphosphonates affect the differentiation into adipocytes. Therefore, this study was aimed... -
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- Streptozotocin-induced Diabetes Increases the Adiponectin-mediated AMP-activated Protein Kinase Cascade in the Hippocampus of Mice
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Yi CO, Jeon BT, Kim YH, Jung TS, Lee DH, Kim HJ, Kang SS, Cho GJ, Choi WS, Roh GS
- KMID: 1472486
- Korean J Anat.
- 2009 Sep;42(3):141-147.
Adiponectin is an adipocyte-derived protein with anti-diabetic and anti-angiogenesis properties that improves both glucose metabolism and insulin resistance via the adenosine monophosphate-activated protein kinase (AMPK) cascade. Diabetic cognitive deficits are... -
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- Effects of fermented blueberry liquid in high-fat diet-induced obese C57BL/6J mice
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Jeon JH, Kim B, Mun EG, Cha YS, Yu OK
- KMID: 2401011
- J Nutr Health.
- 2017 Dec;50(6):543-551.
- doi: 10.4163/jnh.2017.50.6.543
PURPOSE: The objective of the present study was to determine whether fermentation can increase the protective effects of blueberry liquid in a high-fat diet-induced obese mice model. METHODS: Male C57BL/6J mice... -
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