- Molecular Cloning of Human 14-3-3 cDNA with CD3 Zeta Peptide Containing Phosphosering Tag
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Kang JS
- KMID: 1928283
- Korean J Immunol.
- 1998 Sep;20(3):317-323.
14-3-3 proteins are highly conserved proteins of about 29 kDa and have a minimum of seven isoforms. 14- 3-3 proteins interact with many signalling proteins by the recognition of phosphoserine.... -
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- Expression of 14-3-3 proteins and Bax in the placenta of preeclampsia
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Park JK, Kim SI, Paik WY
- KMID: 2077758
- Korean J Obstet Gynecol.
- 2007 Jun;50(6):858-864.
OBJECTIVE: Purpose of our study was to examine the expression level of 14-3-3 proteins and Bcl-2 family and to estimate the interaction between 14-3-3 proteins and Bcl-2 family in normal... -
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- Production of Monoclonal Antibody Against Human 14 - 3 - 3 Zeta Isoform Expressed in Escherichia coli
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Lim BU, Kang JS, Kim JW, Choi NJ
- KMID: 2083005
- Korean J Immunol.
- 1997 Sep;19(3):391-398.
14-3-3 proteins are cytoplasmic proteins of about 29 kDa and have a minimum of seven isoforms. This protein is important in signal transduction with the ability of binding with phosphoserine... -
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- Knockdown of 14-3-3zeta enhances radiosensitivity and radio-induced apoptosis in CD133+ liver cancer stem cells
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Lee YK, Hur W, Lee SW, Hong SW, Kim SW, Choi JE, Yoon SK
- KMID: 2155342
- Exp Mol Med.
- 2014 Feb;46(2):e77.
- doi: 10.1038/emm.2013.151
14-3-3zeta is related to many cancer survival cellular processes. In a previous study, we showed that silencing 14-3-3zeta decreases the resistance of hepatocellular carcinoma (HCC) to chemotherapy. In this study,... -
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- Immunohistochemical study of 14-3-3-sigma and -zeta in ovarian cancer
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Park JK, Shin JK, Choi WJ, Lee SA, Lee JH, Paik WY
- KMID: 1979448
- Korean J Gynecol Oncol.
- 2005 Jun;16(2):113-122.
OBJECTIVE: To evaluate the expression level, localization and distribution of 14-3-3sigma and zeta proteins in human ovarian epithelial carcinoma cells. METHODS: Epithelial carcinoma, benign epithelial tumor and normal ovarian tissues... -
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- A Case of Steroid Responsive Encephalopathy with Positive 14-3-3 Protein in CSF
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Lee JS, Park K, Choi JC, Kang SY, Kang JH
- KMID: 2343313
- J Korean Neurol Assoc.
- 2008 Feb;26(1):63-66.
Encephalopathy is a term for any diffuse disease of brain that alters brain function or structure with very different etiologies and prognoses. There are some reports that steroids have good... -
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- Steroid-Responsive Recurrent Encephalopathy Associated with Subacute Thyroiditis
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Chung YJ, Park KY, Ahn J, Ha SY, Youn YC
- KMID: 2287671
- J Clin Neurol.
- 2008 Dec;4(4):167-170.
- doi: 10.3988/jcn.2008.4.4.167
BACKGROUND: Steroid-responsive encephalopathy associated with subacute thyroiditis has, to our knowledge, not been reported previously. CASE REPORT: A 49-year-old woman was found collapsed and brought to our institution with decreased... -
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- White Matter Lesions in a Patient With Creutzfeldt-Jakob Disease
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Lee HS, Park HY, Chang H
- KMID: 2188244
- J Korean Geriatr Soc.
- 2013 Dec;17(4):259-262.
- doi: 10.4235/jkgs.2013.17.4.259
This is a report of a patient with Creutzfeldt-Jakob disease. The 67-year-old male first developed partial and secondary generalized tonic-clonic seizures. He was disoriented and could not perform calculations nor... -
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- 14-3-3epsilon protein increases matrix metalloproteinase-2 gene expression via p38 MAPK signaling in NIH3T3 fibroblast cells
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Lee EK, Lee YS, Lee H, Choi CY, Park SH
- KMID: 1058019
- Exp Mol Med.
- 2009 Jul;41(7):453-461.
- doi: 10.3858/emm.2009.41.7.050
One of the 14-3-3 protein isoforms, 14-3-3epsilon, was previously shown to be increased during skin aging. We suggest here a possible role for the 14-3-3epsilon protein in skin aging by... -
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- Real-Time Quaking-Induced Conversion Analysis for the Diagnosis of Sporadic Creutzfeldt-Jakob Disease in Korea
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Park JH, Choi YG, Lee YJ, Park SJ, Choi HS, Choi KC, Choi EK, Kim YS
- KMID: 2364926
- J Clin Neurol.
- 2016 Jan;12(1):101-106.
- doi: 10.3988/jcn.2016.12.1.101
BACKGROUND AND PURPOSE: The level of 14-3-3 protein in the cerebrospinal fluid (CSF) is increased in Creutzfeldt-Jakob disease (CJD) patients, which has led to it being used as a clinical... -
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- Hashimoto's Encephalopathy with Positive 14-3-3 Protein in the Cerebrospinal Fluid and Atypical Course Mimicking Creutzfeldt-Jakob Disease
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Yoon JE, Kim JS, Lee KB, Roh H, Ahn MY
- KMID: 2442936
- Dement Neurocogn Disord.
- 2015 Dec;14(4):172-175.
- doi: 10.12779/dnd.2015.14.4.172
BACKGROUND: Creutzfeldt-Jakob disease (CJD) shares common clinical features with Hashimoto's encephalopathy (HE). The 14-3-3 protein is a relatively sensitive and specific marker of CJD but is not commonly detected in... -
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- Expression of the 14-3-3 sigma Protein and Methylation Status of the 14-3-3 sigma gene in Biliary Neoplasms
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Song DE, Jang SJ, Kim JS, Lee SS, Kim MH, Lee SG, Lee YJ, Park HJ, Shim YH, Yu E
- KMID: 1593154
- Korean J Pathol.
- 2006 Feb;40(1):9-16.
BACKGROUND: The 14-3-3 sigma (sigma) protein has a negative regulatory role in the cell cycle progression of the. Down-regulation or overexpression of the 14-3-3 sigma protein has been reported in... -
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- 14-3-3ζ Overexpression is Associated with Poor Prognosis in Ovarian Cancer
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Kim HJ, Sung SH, Kim CY, Bae MK, Cho MS, Kim YH, Kim SC, Ju W
- KMID: 2418848
- Yonsei Med J.
- 2018 Jan;59(1):51-56.
- doi: 10.3349/ymj.2018.59.1.51
PURPOSE: 14-3-3ζ regulates cell signaling, cell cycle progression, and apoptosis, and its overexpression is associated with disease recurrence and poor clinical outcomes in some solid tumors. However, its clinicopathological role... -
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- Repeated electroconvulsive seizure induces c-Myc down-regulation and Bad inactivation in the rat frontal cortex
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Jeon WJ, Kim SH, Seo MS, Kim Y, Kang UG, Juhnn YS, Kim YS
- KMID: 1094123
- Exp Mol Med.
- 2008 Aug;40(4):435-444.
- doi: 10.3858/emm.2008.40.4.435
Repeated electroconvulsive seizure (ECS), a model for electroconvulsive therapy (ECT), exerts neuroprotective and proliferative effects in the brain. This trophic action of ECS requires inhibition of apoptotic activity, in addition... -
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- Neurosyphilis Mimicking Creutzfeldt-Jakob Disease
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Jang JW, Park JH, Eo YJ, Kim SH, Choi KH, Yi S, Park YH, Kim S
- KMID: 2442845
- Dement Neurocogn Disord.
- 2016 Dec;15(4):170-173.
- doi: 10.12779/dnd.2016.15.4.170
BACKGROUND: As rapidly progressive dementia (RPD), general paresis and Creutzfeldt-Jakob disease (CJD) may have overlapping clinical presentation due to a wide variety of clinical manifestations. CASE REPORT: A 57-year-old man presented... -
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- A case of Creutzfeldt-Jakob disease in a patient on hemodialysis
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Suh SH, Choi YH, Kim CS, Choi JS, Park JW, Bae EH, Ma SK, Kim BC, Kim SW
- KMID: 2224331
- Kidney Res Clin Pract.
- 2012 Mar;31(1):76-78.
We report an unusual case of probable Creutzfeldt-Jakob disease (CJD) in hemodialysis patient. A woman 59 years of age with a past history of hypertension and end-stage renal disease presented... -
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- A Case of Heidenhain Variant of Sporadic Creutzfeldt-Jakob Disease
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Kim DH, Kim SY, Yang YS, Jeong SH, Kim JS, Hwang JM
- KMID: 2337675
- J Korean Ophthalmol Soc.
- 2008 Sep;49(9):1548-1552.
PURPOSE: To report a case of the Heidenhain variant of sporadic Creutzfeldt-Jakob disease (CJD), predominantly characterized by visual impairment at onset. CASE SUMMARY: History-taking, ophthalmologic examination, neurologic examination, cerebrospinal fluid examination... -
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- zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 acting on 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells
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Yee SB, Baek SJ, Park HT, Jeong SH, Jeong JH, Kim TH, Kim JM, Jeong BK, Park BS, Kwon TK, Yoon I, Yoo YH
- KMID: 1115941
- Exp Mol Med.
- 2006 Dec;38(6):634-642.
In a preliminary study, we found that benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone (zVAD- fmk), unlike Boc-aspartyl(OMe)-fluoromethylketone (BocD-fmk), at usual dosage could not prevent genistein-induced apoptosis of p815 mastocytoma cells. This study was undertaken to... -
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- Proteomic analyses of cervical cancer tissues by two-dimensional gel electrophoresis and mass spectrometry
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Lee SH, Bae SM, Kim OK, Kim HJ, Park EK, Lee HN, Kim YW, Ro DY, Lee JM, Namkoong S, Cho YL, Nam GH, Han BD, Kim YW, Kim CK, Ahn WS
- KMID: 2272627
- Korean J Obstet Gynecol.
- 2005 Jul;48(7):1686-1697.
OBJECTIVE: Comparison of protein expressions by two-dimensional gel electrophoresis (2-DE) in normal cervix and squamous cell carcinoma tissues in Korean women. METHODS: Normal cervix and squamous cell carcinoma tissues were solubilized... -
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- Neurologists' Awareness and Preparedness on Prion Diseases in Korea
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Jang JW, Park YH, Lim JS, Park SC, Cheong HK, Kim JE, Kim S
- KMID: 2222356
- Dement Neurocogn Disord.
- 2013 Mar;12(1):9-20.
- doi: 10.12779/dnd.2013.12.1.9
BACKGROUND: Creutzfeldt-Jakob disease (CJD) is very rare human prion disease. But, neurologists take a key role in diagnosis, surveillance and management of the cases because of its complexity and difficulty... -
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