- Regulation of Wnt signaling by protein-protein interaction and post-translational modifications
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Kikuchi A, Kishida S, Yamamoto H
- KMID: 1105271
- Exp Mol Med.
- 2006 Feb;38(1):1-10.
The Wnt signaling pathway is conserved in various species from worms to mammals, and plays important roles in cellular proliferation, differentiation, and migration. Wnt stabilizes cytoplasmic beta-catenin and then the... -
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- Modulation of the Transcriptional Activity of Peroxisome Proliferator-Activated Receptor Gamma by Protein-Protein Interactions and Post-Translational Modifications
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Kim TH, Kim MY, Jo SH, Park JM, Ahn YH
- KMID: 1727863
- Yonsei Med J.
- 2013 May;54(3):545-559.
- doi: 10.3349/ymj.2013.54.3.545
Peroxisome proliferator-activated receptor gamma (PPARgamma) belongs to a nuclear receptor superfamily; members of which play key roles in the control of body metabolism principally by acting on adipose tissue. Ligands... -
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- Overexpression of nicotinamide N-methyltransferase in gastric cancer tissues and its potential post-translational modification
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Lim BH, Cho BI, Kim YN, Kim JW, Park ST, Lee CW
- KMID: 1098079
- Exp Mol Med.
- 2006 Oct;38(5):455-465.
Gastric cancer is one of the most common cancers worldwide. The purpose of this study was to find out potential markers for gastric cancer. Tumor and normal tissues from 152... -
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- Intracellular trafficking and metabolic turnover of yeast prepro-alpha-factor-SRIF precursors in GH3 cells
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Lee MA, Cheong KH, Shields D, Park SD, Hong SH
- KMID: 931879
- Exp Mol Med.
- 2002 Sep;34(4):285-293.
Chimeric genes coding for prepro region of yeast alpha-factor and anglerfish SRIF were expressed in rat GH3 cells to determine whether yeast signals could regulate hormone processing in mammalian... -
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- Granulocyte Macrophage Colony-Stimulating Factor May Modulate the Post-transcription Pathway of Interleukin-6 Expression in Prostate Carcinoma Cells
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Kim TH, Oh SY, Kim YS, Lee MK, Kim HS, Myung SC
- KMID: 1786852
- J Korean Med Sci.
- 2008 Feb;23(1):94-97.
- doi: 10.3346/jkms.2008.23.1.94
Interleukin-6 (IL-6) can stimulate a variety of tumors including prostatic carcinoma. Research has recently shown that IL-6 may act to stimulate the progression of prostatic cancer. To date, little research... -
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- Nitric oxide suppresses inducible nitric oxide synthase expression by inhibiting post-translational modification of I kappa B
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Chang K, Lee SJ, Cheong I, Billiar TR, Chung HT, Han JA, Kwon YG, Ha KS, Kim YM
- KMID: 1094075
- Exp Mol Med.
- 2004 Aug;36(4):311-324.
The expression of inducible nitric oxide synthase (iNOS) is a critical factor in both normal physiological functions and the pathogenesis of disease. This study was undertaken to determine the molecular... -
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- Nur77 upregulates HIF-alpha by inhibiting pVHL-mediated degradation
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Kim BY, Kim H, Cho EJ, Youn HD
- KMID: 1103590
- Exp Mol Med.
- 2008 Feb;40(1):71-83.
- doi: 10.3858/emm.2008.40.1.71
In this study, we investigated the role of Nur77, an orphan nuclear receptor, in HIF-alpha transcriptional activity. We found that Nur77 associates and stabilizes HIF-1alpha via indirect interaction. Nur77 was... -
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