- RNA Interference in Functional Genomics and Medicine
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Kim VN
- KMID: 2157643
- J Korean Med Sci.
- 2003 Jun;18(3):309-318.
- doi: 10.3346/jkms.2003.18.3.309
RNA interference (RNAi) is the sequence-specific gene silencing induced by double-stranded RNA (dsRNA). Being a highly specific and efficient knockdown technique, RNAi not only provides a powerful tool for functional... -
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- Perspective beyond Cancer Genomics: Bioenergetics of Cancer Stem Cells
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Ishii H, Doki Y, Mori M
- KMID: 1071410
- Yonsei Med J.
- 2010 Sep;51(5):617-621.
- doi: 10.3349/ymj.2010.51.5.617
Although the notion that cancer is a disease caused by genetic and epigenetic alterations is now widely accepted, perhaps more emphasis has been given to the fact that cancer is... -
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- Comparison of Functional Gene Annotation of Toxascaris leonina and Toxocara canis using CLC Genomics Workbench
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Kim KU, Park SK, Kang SA, Park MK, Cho MK, Jung HJ, Kim KY, Yu HS
- KMID: 1792143
- Korean J Parasitol.
- 2013 Oct;51(5):525-530.
The ascarids, Toxocara canis and Toxascaris leonina, are probably the most common gastrointestinal helminths encountered in dogs. In order to understand biological differences of 2 ascarids, we analyzed gene expression... -
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- The Path to Clinical Proteomics Research: Integration of Proteomics, Genomics, Clinical Laboratory and Regulatory Science
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Boja ES, Rodriguez
- KMID: 1094342
- Korean J Lab Med.
- 2011 Apr;31(2):61-71.
- doi: 10.3343/kjlm.2011.31.2.61
Better biomarkers are urgently needed to cancer detection, diagnosis, and prognosis. While the genomics community is making significant advances in understanding the molecular basis of disease, proteomics will delineate the... -
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- Genomic assays for Epstein-Barr virus-positive gastric adenocarcinoma
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Gulley ML
- KMID: 2155399
- Exp Mol Med.
- 2015 Jan;47(1):e134.
- doi: 10.1038/emm.2014.93
A small set of gastric adenocarcinomas (9%) harbor Epstein-Barr virus (EBV) DNA within malignant cells, and the virus is not an innocent bystander but rather is intimately linked to pathogenesis... -
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- Integrative epigenomic and genomic analysis of malignant pheochromocytoma
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Sandgren J, Andersson , Rada-Iglesias A, Enroth S, Akerstrom , Dumanski J, Komorowski J, Westin G, Wadelius C
- KMID: 1104209
- Exp Mol Med.
- 2010 Jul;42(7):484-502.
- doi: 10.3858/emm.2010.42.7.050
Epigenomic and genomic changes affect gene expression and contribute to tumor development. The histone modifications trimethylated histone H3 lysine 4 (H3K4me3) and lysine 27 (H3K27me3) are epigenetic regulators associated to... -
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