- The Effect of HIF-1alpha siRNA on Growth and Chemosensitivity of Mia-paca Cell Line
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Yang L, Kang WK
- KMID: 1084504
- Yonsei Med J.
- 2008 Apr;49(2):295-300.
- doi: 10.3349/ymj.2008.49.2.295
PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) primarily mediates the hypoxic response. HIF-1alpha induction by various stimuli contributes to cell proliferation and survival. To investigate the effect of HIF-1alpha, we used small interfering... -
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- Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model
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Yoo SW, Kim SS, Lee SY, Lee HS, Kim HS, Lee YD, Suh-Kim H
- KMID: 1094118
- Exp Mol Med.
- 2008 Aug;40(4):387-397.
- doi: 10.3858/emm.2008.40.4.387
Mesenchymal stem cells (MSCs) secrete bioactive factors that exert diverse responses in vivo. In the present study, we explored mechanism how MSCs may lead to higher functional recovery in the... -
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- Increased Intestinal Epithelial Cell Turnover and Intestinal Motility in Gymnophalloides seoi-Infected C57BL/6 Mice
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Lee SH, Jung BK, Park JH, Shin EH, Chai JY
- KMID: 1792181
- Korean J Parasitol.
- 2014 Jun;52(3):273-280.
The changing patterns of goblet cell hyperplasia, intestinal epithelial cell turnover, and intestinal motility were studied in ICR and C57BL/6 mice infected with Gymnophalloides seoi (Digenea: Gymnophallidae). Whereas ICR mice... -
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- MicroRNA-103a-3p controls proliferation and osteogenic differentiation of human adipose tissue-derived stromal cells
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Kim DS, Lee SY, Lee JH, Bae YC, Jung JS
- KMID: 2155426
- Exp Mol Med.
- 2015 Jul;47(7):e172.
- doi: 10.1038/emm.2015.39
The elucidation of the molecular mechanisms underlying the differentiation and proliferation of human adipose tissue-derived stromal cells (hADSCs) represents a critical step in the development of hADSCs-based cellular therapies. To... -
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- The roles of glycosphingolipids in the proliferation and neural differentiation of mouse embryonic stem cells
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Jung JU, Ko K, Lee DH, Ko K, Chang KT, Choo YK
- KMID: 1099869
- Exp Mol Med.
- 2009 Dec;41(12):935-945.
- doi: 10.3858/emm.2009.41.12.099
Glycosphingolipids including gangliosides play important regulatory roles in cell proliferation and differentiation. UDP-glucose:ceramide glucosyltransferase (Ugcg) catalyze the initial step in glycosphingolipids biosynthesis pathway. In this study, Ugcg expression was reduced... -
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- Enhanced proliferation and differentiation of Oct4- and Sox2-overexpressing human adipose tissue mesenchymal stem cells
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Han SM, Han SH, Coh YR, Jang G, Chan Ra J, Kang SK, Lee HW, Youn HY
- KMID: 2155366
- Exp Mol Med.
- 2014 Jun;46(6):e101.
- doi: 10.1038/emm.2014.28
Mesenchymal stem cells (MSCs) are attractive candidates for clinical repair or regeneration of damaged tissues. Oct4 and Sox2, which are essential transcription factors for pluripotency and self-renewal, are naturally expressed... -
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- Grading of Histology, Expression of Apoptosis and Cell Proliferation in Gastric Mucosa Adjacent to Gastric Adenoma or Adenocarcinoma
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Jung JT, Lee CH, You SS, Ha HK, Bae JS, Kwon JG, Kim EY, Kim HG, Cho CH, Shin IH
- KMID: 772843
- Korean J Gastroenterol.
- 2005 Oct;46(4):269-275.
BACKGROUND/AIMS: Helicobacter pylori (H. pylori) infection can lead to gastric adenoma and carcinoma through atrophic gastritis and intestinal metaplasia. Imbalance between apoptosis and proliferation may play a role in gastric... -
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- Expression of c-FLIP in Gastric Cancer and its Relation to Tumor Cell Proliferation and Apoptosis
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Ryang DY, Joo YE, Chung KM, Lim SR, Jeong HK, Kim HI, Lee WS, Park CH, Kim HS, Choi SK, Rew JS, Lee JH, Park CS
- KMID: 1776678
- Korean J Intern Med.
- 2007 Dec;22(4):263-269.
- doi: 10.3904/kjim.2007.22.4.263
BACKGROUND: The expression of c-FLIP (cellular Fas-associated death domain-like interleukin-1 beta-converting enzyme (FLICE)-inhibitory protein), which is a member of the family of inhibitors of apoptosis, has been associated with... -
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- TGF-beta1-induced PINCH-1-ILK-alpha-parvin complex formation regulates mesangial cell proliferation and hypertrophy
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Kim SM, Kim N, Lee S, Kim DK, Lee YM, Ahn SH, Song JH, Choi BK, Wu C, Jung KY
- KMID: 756075
- Exp Mol Med.
- 2007 Aug;39(4):514-523.
TGF-beta1-induced glomerular mesangial cell (GMC) injury is a prominent characteristic of renal pathology in several kidney diseases, and a ternary protein complex consisting of PINCH-1, integrin-linked kinase (ILK) and alpha-parvin... -
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- Immunologic properties of differentiated and undifferentiated mesenchymal stem cells derived from umbilical cord blood
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Lee HJ, Kang KS, Kang SY, Kim HS, Park SJ, Lee SY, Kim KD, Lee HC, Park JK, Paik WY, Lee L, Yeon SC
- KMID: 2413127
- J Vet Sci.
- 2016 Sep;17(3):289-297.
- doi: 10.4142/jvs.2016.17.3.289
The expression of immunogenic markers after differentiation of umbilical cord blood (UCB)-derived mesenchymal stem cells (MSC) has been poorly investigated and requires extensive in vitro and in vivo testing for... -
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- Endothelin A Receptor Blockade Influences Apoptosis and Cellular Proliferation in the Developing Rat Kidney
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Yoo KH, Yim HE, Jang GY, Bae IS, Choi BM, Hong YS, Lee JW
- KMID: 1794420
- J Korean Med Sci.
- 2009 Feb;24(1):138-145.
- doi: 10.3346/jkms.2009.24.1.138
Endothelin systems are believed to play important roles in the emergence and maintenance of functions of various organs during perinatal development, including the kidney. The present study was designed to... -
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- TRPC3 cation channel plays an important role in proliferation and differentiation of skeletal muscle myoblasts
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Woo JS, Cho CH, Kim DH, Lee EH
- KMID: 983954
- Exp Mol Med.
- 2010 Sep;42(9):614-627.
- doi: 10.3858/emm.2010.42.9.061
During membrane depolarization associated with skeletal excitation-contraction (EC) coupling, dihydropyridine receptor [DHPR, a L-type Ca2+ channel in the transverse (t)-tubule membrane] undergoes conformational changes that are transmitted to ryanodine receptor... -
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- Enhanced skin wound healing by a sustained release of growth factors contained in platelet-rich plasma
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Yang HS, Shin J, Bhang SH, Shin JY, Park J, Im GI, Kim CS, Kim BS
- KMID: 1025165
- Exp Mol Med.
- 2011 Nov;43(11):622-629.
- doi: 10.3858/emm.2011.43.11.070
Platelet-rich plasma (PRP) contains growth factors that promote tissue regeneration. Previously, we showed that heparin-conjugated fibrin (HCF) exerts the sustained release of growth factors with affinity for heparin. Here, we... -
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