Korean J Med Mycol.  1998 Jun;3(1):63-66.

Primary Cutaneous Cryptococcosis Treated with Itraconazole

• Jeong MC
• Park SH
• Kim KJ
• Kang HJ

Abstract

In most instances, Cryptococcosis is a systemic disease caused by the yeast-like fungus Cryptococcus neoformans through respiratory tract. The organism is worldwide in its distribution, is saprophytic, and is found in soil and in pigeon excretion. Primary cutaneous cryptococcosis is rare; skin lesion is the sole manifestation of the disease without preceding generalized or cerebrospinal involvement. We report a case of primary cutaneous crytococcosis. The patient was a 53-year-old female, who had had an erythematous ulcerated lesion with swollen border on the dorsum of right wrist. Histopathologic examination showed typical spores with capsules. Other physical examinations and laboratory findings were within normal limit. The lesion was successfully treated with oral itraconazole (200mg/dayx7weeks).

Keyword

Cutaneous cryptococcosis; Itraconazole

MeSH Terms

Capsules
Columbidae
Cryptococcosis*
Cryptococcus neoformans
Female
Fungi
Humans
Itraconazole*
Middle Aged
Physical Examination
Respiratory System
Skin
Soil
Spores
Ulcer
Wrist
Capsules
Itraconazole
Soil