Yonsei Med J.  2015 May;56(3):719-725. 10.3349/ymj.2015.56.3.719.

Prevalence of Vitiligo and Associated Comorbidities in Korea

Affiliations
  • 1Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. oddung93@yuhs.ac
  • 2Department of Dermatology, Kyung Hee University School of Medicine, Seoul, Korea.
  • 3Department of Dermatology, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 4Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.
  • 5Department of Dermatology, Dong-A University College of Medicine, Busan, Korea.
  • 6Department of Dermatology, Inha University School of Medicine, Incheon, Korea.
  • 7Department of Dermatology, CHA Bundang Medical Center, CHA University, Bundang, Korea.
  • 8Whiteline Skin Clinic, Changwon, Korea.
  • 9Department of Dermatology, Dongguk University Ilsan Hospital, Dongguk University Graduate School of Medicine, Goyang, Korea.
  • 10Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
  • 11Department of Dermatology, Soonchunhyang University College of Medicine, Seoul, Korea.
  • 12Department of Dermatology, School of Medicine, Gachon University, Incheon, Korea.
  • 13Korea Institute of Vitiligo Research & Drs. Woo and Hann's Skin Center, Seoul, Korea.
  • 14Department of Dermatology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea. cjpark777smp@gmail.com

Abstract

PURPOSE
Vitiligo prevalence and its associated comorbidities rate have been reported variably among different populations. We aimed to determine the prevalence of vitiligo in Korea along with the baseline rate of comorbidities and compared the risks to the general population using hospital visit information of the total population in Korea.
MATERIALS AND METHODS
We assessed demographic characteristics of vitiligo patients in Korean population from 2009 to 2011 in a nationwide data from Health Insurance Review Assessment Service. Patients who had at least one visit to Korea's primary, secondary, or tertiary referral hospitals with International Classification of Diseases, 10th Revision, Clinical Modification diagnosis code for vitiligo were identified. As a supplementary study, comorbidities associated with vitiligo were selected for further review to calculate relative risks compared to the general population.
RESULTS
The annual prevalence of vitiligo determined by hospital-visiting rate in Korea was 0.12% to 0.13% over a three year period. In sync with other previous epidemiological studies, there was bimodal distribution among the age groups and no difference between genders. Also, vitiligo in Korean population was associated with various autoimmune/non-autoimmune diseases such as thyroiditis, atopic dermatitis, and psoriasis.
CONCLUSION
This study was by far the most comprehensive review on prevalence of vitiligo using a data of total population in Korea. The prevalence is within a range of those reported in previous literatures, and increased risk of comorbidities such as thyroid diseases and psoriasis in vitiligo might aid clinicians in the initial work up of vitiligo patients and concurrent follow ups.

Keyword

Vitiligo; epidemiology; prevalence; autoimmune diseases

MeSH Terms

Adult
Aged
Autoimmune Diseases/*epidemiology/immunology
Comorbidity
Diabetes Mellitus, Type 1/epidemiology
Female
Humans
Male
Middle Aged
Population Surveillance
Prevalence
Republic of Korea/epidemiology
Socioeconomic Factors
Thyroid Diseases/epidemiology
Vitiligo/*epidemiology

Figure

  • Fig. 1 Age distribution of vitiligo patients in Korean population.


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