Korean J Dermatol.  1976 Dec;14(4):325-334.

Mycological and Clinical Observation on Dermatophytosis

• Kim BS
• Suh SB

Abstract

this study was first initiated to compare the effectiveness of the KOH mount versus actual culturing from 1928 skin scrapings obtained frorn December, 1975 to August, 1976 in Daegu area. Second, changes in both clicical patterns and fungal flora isilated among the causative organisms were observed and following results were obtained . The KOH mount reparte;d a higher number of positive cases, when compared with the culture method. Covered areas of the body reported higher KOH positive rates than exposed areas, while cultures from the finger and toe-nails r."ported unusually low positive rates. In 51. 3% of the cases, both culture and KOH rnount were pasitive. The positive coincidence rate was found to be highest with the lesions frorn the scalp, buttock and groin, and lowest with lesions from the hands and feet. The positive KOH scrapings when cultured, showed a 10. 3% negative rate while the negative KOH scrapings reported a 7. 3%. positive culture rate. The rate of culture contamination was highest in KOH negative cases and also highest among finger and toe-nail lesions. Weather was also thought to be a factor: the higher the temperature, the lower the frequency of contamination. The 1138 strains isolated in 1976 were compared to a similar study done between 1957---1959, the following result., were observed: Trubrum has markedly increased while T. ferrugineum has significantly decreased with M. gypseum reported for the first time in Korea. Although most of these species were fairly equally distributed thrcughout the urban and rural areas, M. canis and M. gypseum were lirnited to the urban areas. Compared to 1959 changes in the causative organisms rate of the following dermatophytosis were observed In T. pedis, T. corporis, T. manus and T. Unguiurn, T. rubrum was reported as the predorninant causative agent and t.he second most prominent causative agent was T. mentaprophytes. In. T. cruris, T, rubum. was also repoted as the predoniinant causative agent with E. floccosurn the second whiile in T. capitis, T. ferrugineum remained the predominant causative agent, The frequeny of dernatophytosis was reported as follows: Tinea nf the nands and feet reported the highest incidence, T. pedis alone accounted for 38. 8% of all dermatophytosis while T, cruris was second 21.0% Compared to the previously study T. capitis decreased significantly. The majority of cases were found to be in the ag group(20~39 years) 68.4%. T. capitis and T. cruris were reported predominatly in males while similar results were reported with T. pedis. T. rnanus and T. unguium in females. The monthly distribution of T. capitis, T. corporis and T, cruris remained fairly consiant while T. pedis and I manus greatly increased during the liottcr months KIay to August. Coexistence of dermatophytosis preferred females to males and T.cruris infected from T. pedis was also common in males. On second experiment we extended the length of application to 15 days and the number of sujects to 15 persons. There developed erytherna in 1 case after 13 days of application and the others never showed erythema after 15 days of application, whereas with 2% soap solution erythema developed in 2 cases in 24 hours, 9 cases by 48 hours and 13 cases by 72 hours of application. The other 2 cases never showed erythema after 15 days of application. With above result there is no need to calculata IT as Kligman already mentioned. It is apparent that topically applied Ginseng saponin is essentially non-irritant material to the skin.

MeSH Terms

Buttocks
Daegu
Erythema
Female
Fingers
Foot
Groin
Hand
Humans
Incidence
Korea
Male
Panax
Saponins
Scalp
Skin
Soaps
Tinea*
Weather
Saponins
Soaps