J Korean Neurol Assoc.  2015 Aug;33(3):221-225. 10.17340/jkna.2015.3.17.

Acute Hemorrhagic Leukoencephalopathy in a Patient with Influenza A and B Coinfection

• Park DY
• Yoon DY
• Kwon JS
• Jhang Y

• KMID: 2184612
• DOI: http://doi.org/10.17340/jkna.2015.3.17

Abstract

Acute hemorrhagic leukoencephalopathy is a rare condition associated with the influenza virus, but the role of influenza in this condition has not been clarified. We experienced a patient with influenza A and B virus co-infection who initially presented mild gastrointestinal symptoms and rapidly progressed to coma. Magnetic resonance imaging showed severe brain edema and multiple intracranial hemorrhagic lesions. The patient was treated with oseltamivir and corticosteroid, and her clinical course improved without neurological sequelae.

Keyword

Influenza; Acute hemorrhagic leukoencephalopathy; Magnetic resonance imaging

MeSH Terms

Brain Edema
Coinfection*
Coma
Herpesvirus 1, Cercopithecine
Humans
Influenza, Human*
Leukoencephalopathies*
Magnetic Resonance Imaging
Orthomyxoviridae
Oseltamivir
Oseltamivir